{"active_ingredient":["Active ingredient Stannous fluoride 0.454% (0.14% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. & older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. do not swallow children under 12 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e4b187-6e75-bee3-e063-6294a90af843","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, sodium lauryl sulfate, carrageenan, sodium gluconate, flavor, xanthan gum, zinc citrate, stannous chloride, sodium saccharin, sodium hydroxide, titanium dioxide"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis"],"keep_out_of_reach_of_children":["Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Premium Plus Breath Bacteria Blast"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-912-70","69423-912-52"],"product_ndc":["69423-912"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["47e4b187-6e75-bee3-e063-6294a90af843"],"spl_set_id":["c3f1d477-6dd8-0ac4-e053-2a95a90a3742"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 147 g Tube Carton Crest ® plus™ PREMIUM WITH STAND UP FLIP CAP FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS NET WT 5.2 OZ (147 g) ACTIVE FOAM +WHITENING BREATH BACTERIA BLAST DEFENDS AGAINST MILLIONS OF BAD BREATH BACTERIA* clean mint 69423912"],"purpose":["Purposes Anticavity, antigingivitis toothpaste"],"questions":["Questions? 1-800-594-4158"],"recent_major_changes":[""],"set_id":"c3f1d477-6dd8-0ac4-e053-2a95a90a3742","spl_product_data_elements":["Crest Premium Plus Breath Bacteria Blast Stannous Fluoride HYDRATED SILICA SORBITOL ZINC CITRATE WATER SODIUM LAURYL SULFATE SODIUM GLUCONATE CARRAGEENAN SACCHARIN SODIUM XANTHAN GUM SODIUM HYDROXIDE STANNOUS CHLORIDE TITANIUM DIOXIDE STANNOUS FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"storage_and_handling":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist this Crest is specially formulated to help prevent staining see your dentist regularly"],"version":"5","warnings":["Warnings Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}