{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e4b187-6e76-bee3-e063-6294a90af843","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, alcohol (0.7%), sodium saccharin, xanthan gum, glycerin, cellulose gum, carbomer, polysorbate 80, sodium benzoate, cetylpyridinium chloride, benzoic acid, titanium dioxide, blue 1, yellow 5"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Premium Plus Active Foam Whitening scope"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-949-52","69423-949-72","69423-949-35"],"product_ndc":["69423-949"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e4b187-6e76-bee3-e063-6294a90af843"],"spl_set_id":["c72b15e0-e69c-65fc-e053-2a95a90a54c8"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 147 g Tube Carton Crest plus PREMIUM WITH FLIP CAP NET WT 5.2OZ (147 g) ANTICAVITY FLUORIDE TOOTHPASTE ACTIVE FOAM +WHITENING scope KILLS MILLIONS OF BAD BREATH GERMS* minty fresh striped Label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"c72b15e0-e69c-65fc-e053-2a95a90a54c8","spl_product_data_elements":["Crest Premium Plus Active Foam Whitening scope Sodium Fluoride POLYSORBATE 80 SODIUM BENZOATE CETYLPYRIDINIUM CHLORIDE FD&C YELLOW NO. 5 BENZOIC ACID TITANIUM DIOXIDE FD&C BLUE NO. 1 SODIUM ACID PYROPHOSPHATE SODIUM HYDROXIDE XANTHAN GUM SACCHARIN SODIUM SODIUM FLUORIDE FLUORIDE ION CARBOXYPOLYMETHYLENE SORBITOL WATER HYDRATED SILICA SODIUM LAURYL SULFATE ALCOHOL CARBOXYMETHYLCELLULOSE SODIUM"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"9","warnings":["Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}