{"active_ingredient":["Active ingredient Cetylpyridinium chloride 0.07%"],"ask_doctor":["Ask a dentist if symptoms persist or condition worsens after regular use."],"dosage_and_administration":["Directions use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use adults and children 6 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day do not swallow children 6 years to under 12 years of age: supervise use children under 6 years of age: do not use"],"effective_time":"20260108","id":"47e4b20c-da2c-c123-e063-6294a90aaf0b","inactive_ingredient":["Inactive ingredients water, glycerin, flavor, zinc lactate, methylparaben, sodium saccharin, sucralose, propylparaben, poloxamer 407, blue 1"],"indications_and_usage":["Uses helps prevent and reduce plaque and gingivitis helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M022"],"brand_name":["Crest Pro-Health Advantage"],"generic_name":["CETYLPYRIDINIUM CHLORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-893-33","69423-893-31"],"product_ndc":["69423-893"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1100924","1251371"],"spl_id":["47e4b20c-da2c-c123-e063-6294a90aaf0b"],"spl_set_id":["ddcd56fe-25d6-8195-e053-2a95a90a575a"],"substance_name":["CETYLPYRIDINIUM CHLORIDE"],"unii":["D9OM4SK49P"]},"package_label_principal_display_panel":["Crest Pro Health Advantage Rinse 1L ALCOHOL FREE Crest ® PRO-HEALTH™ ADVANTAGE CPC ANTIGINGIVITIS/ANTIPLAQUE ORAL MOUTHWASH 99% GERM KILL AND A HEALTHIER MOUTH* MULTI-PROTECTION SMOOTH MINT REDUCES PLAUE BACTERIA HELPS PREVENT GINGIVITIS FRESHENS BREATH 1 L (33.8 FL OZ) Crest Pro Health Advantage Rinse"],"purpose":["Purpose Antigingivitis/antiplaque"],"questions":["Questions? 1–800–285–9139"],"set_id":"ddcd56fe-25d6-8195-e053-2a95a90a575a","spl_product_data_elements":["Crest Pro-Health Advantage Cetylpyridinium chloride PROPYLPARABEN SUCRALOSE GLYCERIN ZINC LACTATE METHYLPARABEN SACCHARIN SODIUM POLOXAMER 407 WATER FD&C BLUE NO. 1 CETYLPYRIDINIUM CHLORIDE CETYLPYRIDINIUM"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"8","warnings":["Warnings Ask a dentist if symptoms persist or condition worsens after regular use. Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}