{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e4bcee-5026-eff8-e063-6294a90a9a3c","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, sodium lauryl sulfate, flavor, trisodium phosphate, cellulose gum, sodium saccharin, sodium phosphate, carbomer, titanium dioxide"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Fresh and White"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-897-64","69423-897-24","69423-897-29","69423-897-57"],"product_ndc":["69423-897"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e4bcee-5026-eff8-e063-6294a90a9a3c"],"spl_set_id":["f9b31f6b-6b3f-abe0-e053-6294a90acb25"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 161 g Tube Carton CLEANS AND WHITENS TEETH* Crest® FLUORIDE ANTICAVITY TOOTHPASTE NET WT 5.7 oz (161 g) FRESH AND WHITE Peppermint GLEEM™ Paste Crest Fresh and White"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"f9b31f6b-6b3f-abe0-e053-6294a90acb25","spl_product_data_elements":["Crest Fresh and White Sodium Fluoride CARBOXYPOLYMETHYLENE SODIUM PHOSPHATE SORBITOL WATER HYDRATED SILICA SODIUM LAURYL SULFATE SACCHARIN SODIUM CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM TITANIUM DIOXIDE SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","Distr. by Procter & Gamble, Cincinnati, OH 45202"],"version":"5","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}