{"active_ingredient":["Active ingredient Stannous fluoride 0.454% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. do not swallow children under 12 yrs. of age: ask a dentist"],"effective_time":"20260108","id":"47e4dc98-55f0-efbb-e063-6294a90a7f84","inactive_ingredient":["Inactive ingredients glycerin, hydrated silica, water, zinc lactate, sodium lauryl sulfate, trisodium phosphate, flavor, sodium gluconate, sodium saccharin, xanthan gum, cellulose gum, sodium hydroxide, polyethylene, mica, titanium dioxide, blue 1"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis"],"keep_out_of_reach_of_children":["Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Gum Detoxify plus Whitening"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-489-01"],"product_ndc":["37000-489"],"product_type":["HUMAN OTC DRUG"],"rxcui":["416784"],"spl_id":["47e4dc98-55f0-efbb-e063-6294a90a7f84"],"spl_set_id":["63779942-0f6c-11c5-e053-2991aa0a25ab"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - Kit Carton CLINICALLY PROVEN RESULTS IN ONE WEEK Crest ® GUM DETOXIFY + WHITENING™ FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS/WHITENING GEL STEP 1 6X Gum health Improvement in one week* *gingivitis improvement vs. ordinary toothpaste STEP 2 Whiter teeth in 1 week** **improvement vs. ordinary toothpaste 1 TUBE NET WT 4.0 OZ (113 g) & 1 TUBE NET WT 2.3 OZ (65 g) 489"],"purpose":["Purposes Anticavity, antigingivitis toothpaste"],"questions":["Questions? (800) 492-7378"],"set_id":"63779942-0f6c-11c5-e053-2991aa0a25ab","spl_product_data_elements":["Crest Gum Detoxify plus Whitening Stannous Fluoride Crest Gum Detoxifying Treatment Stannous Fluoride HYDRATED SILICA WATER ZINC LACTATE SODIUM LAURYL SULFATE SODIUM GLUCONATE GLYCERIN SACCHARIN SODIUM XANTHAN GUM CARBOXYMETHYLCELLULOSE SODIUM SODIUM HYDROXIDE MICA TITANIUM DIOXIDE FD&C BLUE NO. 1 SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS STANNOUS FLUORIDE FLUORIDE ION Crest Whitening Gel WATER GLYCERIN HYDROGEN PEROXIDE SODIUM ACID PYROPHOSPHATE SUCRALOSE SODIUM HYDROXIDE CARBOXYPOLYMETHYLENE"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati, OH 45202"],"storage_and_handling":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist see your dentist regularly"],"version":"10","warnings":["Warning Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. Directions adults and children 12 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. do not swallow children under 12 yrs. of age: ask a dentist Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist see your dentist regularly Inactive ingredients glycerin, hydrated silica, water, zinc lactate, sodium lauryl sulfate, trisodium phosphate, flavor, sodium gluconate, sodium saccharin, xanthan gum, cellulose gum, sodium hydroxide, polyethylene, mica, titanium dioxide, blue 1"]}