{"active_ingredient":["Active ingredient Cetylpyridinium chloride 0.07%"],"ask_doctor":["Ask a dentist if symptoms persist or condition worsens after regular use."],"dosage_and_administration":["Directions use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use adults and children 6 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day do not swallow children 6 years to under 12 years of age: supervise use children under 6 years of age: do not use"],"effective_time":"20260108","id":"47e4e758-d6de-4e88-e063-6394a90ac40e","inactive_ingredient":["Inactive ingredients water, glycerin, flavor, poloxamer 407, methylparaben, sodium saccharin, propylparaben, blue 1"],"indications_and_usage":["Uses helps prevent and reduce plaque and gingivitis helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M022"],"brand_name":["Crest Pro-Health Multi-Protection Refreshing Clean Mint"],"generic_name":["CETYLPYRIDINIUM CHLORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-451-01","37000-451-03","37000-451-04","37000-451-05","37000-451-06","37000-451-10","37000-451-02","37000-451-11"],"product_ndc":["37000-451"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1100924","1251371"],"spl_id":["47e4e758-d6de-4e88-e063-6394a90ac40e"],"spl_set_id":["8867d791-7e93-4f39-aaaf-bfbee8296fd9"],"substance_name":["CETYLPYRIDINIUM CHLORIDE"],"unii":["D9OM4SK49P"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 500mL Bottle Label ALCOHOL FREE Crest ® PRO-HEALTH ® CPC ANTIGINGIVITIS/ANTIPLAQUE ORAL RINSE CLEAN MINT MULTI-PROTECTION 99% GERM KILL Reduces Plaque Bacteria HELPS PREVENT GINGIVITIS FRESHENS BREATH 500 mL (16.9 FL OZ) 91986694 Label"],"purpose":["Purpose Antigingivitis/Antiplaque"],"questions":["Questions? 1–800–285–9139"],"set_id":"8867d791-7e93-4f39-aaaf-bfbee8296fd9","spl_product_data_elements":["Crest Pro-Health Multi-Protection Refreshing Clean Mint Cetylpyridinium chloride WATER GLYCERIN POLOXAMER 407 METHYLPARABEN SACCHARIN SODIUM PROPYLPARABEN FD&C BLUE NO. 1 CETYLPYRIDINIUM CHLORIDE CETYLPYRIDINIUM"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati OH 45202"],"version":"14","warnings":["Warnings Ask a dentist if symptoms persist or condition worsens after regular use. Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}