{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e4ffad-8c7a-4b7f-e063-6294a90ae121","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, sodium lauryl sulfate, trisodium phosphate, cellulose gum, flavor, sodium phosphate, sodium saccharin, carbomer, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Plus Cavity Protection Cool Mint Gel"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-816-82","69423-816-57"],"product_ndc":["69423-816"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e4ffad-8c7a-4b7f-e063-6294a90ae121"],"spl_set_id":["0813171e-bda5-b004-e063-6394a90ad364"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 161 g Carton ADA ACCEPTED American Dental Association Crest Plus FLUORIDE ANTICAVITY TOOTHPASTE NET WT 5.7 OZ (161 g) CAVITY PROTECTION WITH ACTIVE FLUORIDE Cool Mint Gel Label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"recent_major_changes":[""],"set_id":"0813171e-bda5-b004-e063-6394a90ad364","spl_product_data_elements":["Crest Plus Cavity Protection Cool Mint Gel Sodium Fluoride SACCHARIN SODIUM SODIUM PHOSPHATE, TRIBASIC SORBITOL WATER HYDRATED SILICA SODIUM LAURYL SULFATE SODIUM PHOSPHATE FD&C BLUE NO. 1 CARBOXYMETHYLCELLULOSE SODIUM SODIUM FLUORIDE FLUORIDE ION CARBOXYPOLYMETHYLENE"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati OH 45202 www.crest.com"],"version":"3","warnings":["Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}