{"active_ingredient":["Active ingredient Sodium Fluoride 0.02% (0.01 w/v fluoride ion)"],"dosage_and_administration":["Directions Use twice a day after brushing your teeth with toothpaste. Vigorously swish 10mL (2 teaspoonfuls) of rinse between your teeth for 1 minute and then spit out. Do not swallow the rinse. Do not eat or drink for 30 minutes after rinsing. Instruct children under 12 years of age in good rinsing habits (to minimize swallowing). Supervise children as necessary until capable of using without supervision. Children under 6 years of age: consult a dentist or doctor."],"effective_time":"20260108","id":"47e52d8a-24aa-953f-e063-6294a90affc6","inactive_ingredient":["Inactive ingredients water, glycerin, cetylpyridinium chloride, flavor, sodium saccharin, phosphoric acid, methylparaben, sucralose, poloxamer 407, propylparaben, disodium phosphate, red 33, green 3"],"indications_and_usage":["Uses Aids the prevention of dental cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 12 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M022"],"brand_name":["Crest Pro-Health Advanced Enamel Care"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-745-16","69423-745-33","69423-745-36"],"product_ndc":["69423-745"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"spl_id":["47e52d8a-24aa-953f-e063-6294a90affc6"],"spl_set_id":["1660e7d7-5b8d-8aba-e063-6294a90a50d8"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 473 mL Bottle Label +FLUORIDE Crest PRO-HEALTH ADVANCED ANTICAVITY FLUORIDE MOUTHWASH ENAMEL CARE ALCOHOL FREE IMPORTANT: Read directions for proper use. KILLS BAD BREATH GERMS PROTECTS AGAINST CAVITIES FRESHENDS BREATH REBUILDS WEAKENED ENAMEL CLEANS THE WHOLE MOUTH STRENGTHENS TEETH 1L (33.8 FL OZ) Label"],"purpose":["Purpose Anticavity"],"questions":["Questions? 1–800–862-7442"],"set_id":"1660e7d7-5b8d-8aba-e063-6294a90a50d8","spl_product_data_elements":["Crest Pro-Health Advanced Enamel Care Sodium Fluoride WATER GLYCERIN HYDROGEN PEROXIDE SUCRALOSE POLOXAMER 407 SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati OH 45202"],"version":"4","warnings":["Warnings Keep out of reach of children under 12 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}