{"active_ingredient":["Active ingredient Stannous fluoride 0.454% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. • do not swallow • children under 12 yrs. of age: ask a dentist"],"effective_time":"20260108","id":"47e53483-0dbf-e448-e063-6394a90a6cd1","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, sodium gluconate, sodium lauryl sulfate, carrageenan, sodium citrate, flavor, xanthan gum, cocamidopropyl betaine, zinc citrate, sodium hydroxide, stannous chloride, sodium saccharin, sucralose, titanium dioxide"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis"],"keep_out_of_reach_of_children":["Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Pro-Health Gum Rescue Pro Soothing Clean"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["84126-609-46"],"product_ndc":["84126-609"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["47e53483-0dbf-e448-e063-6394a90a6cd1"],"spl_set_id":["2f10c7ac-eb60-011e-e063-6394a90aca13"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 130 g Tube Carton LARGE SIZE Crest PRO-HEALTH FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS GUM RESCUE ACTIVELY REVERSES WEAK SPOTS, EVEN IN AREAS OF RECESSION SOOTHING CLEANSE CLINICALLY PROVEN BETTER GUM HEALTH NET WT 4.6 OZ (130 g) Label"],"purpose":["Purposes Anticavity, antigingivitis toothpaste"],"questions":["Questions? 1-800-594-4158"],"recent_major_changes":[""],"set_id":"2f10c7ac-eb60-011e-e063-6394a90aca13","spl_product_data_elements":["Crest Pro-Health Gum Rescue Pro Soothing Clean Stannous Fluoride GLYCINE SUCRALOSE HYDRATED SILICA SORBITOL SODIUM CITRATE COCAMIDOPROPYL BETAINE WATER SODIUM LAURYL SULFATE SODIUM GLUCONATE CARRAGEENAN SACCHARIN SODIUM XANTHAN GUM ZINC CITRATE SODIUM HYDROXIDE STANNOUS CHLORIDE TITANIUM DIOXIDE STANNOUS FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"storage_and_handling":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist this Crest is specially formulated to help prevent staining see your dentist regularly"],"version":"5","warnings":["Warnings Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}