{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e55ea2-1115-0daa-e063-6394a90ababc","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, sodium lauryl sulfate, trisodium phosphate, flavor, sodium phosphate, cellulose gum, sodium saccharin, carbomer, titanium dioxide"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Fresh and White"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Procter & Gamble Manufactura, S. de R.L. de C.V."],"package_ndc":["58933-868-02","58933-868-24"],"product_ndc":["58933-868"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e55ea2-1115-0daa-e063-6394a90ababc"],"spl_set_id":["5a1bb1fb-12a5-5fd1-e053-2991aa0a628b"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 68 g Tube Carton CLEANS & WHITENS TEETH* Crest ® FLUORIDE ANTICAVITY TOOTHPASTE NET WT 2.4 OZ (68 g) FRESH AND WHITE Peppermint GLEEM ™ Paste Artwork"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"5a1bb1fb-12a5-5fd1-e053-2991aa0a628b","spl_product_data_elements":["Crest Fresh and White Sodium Fluoride WATER HYDRATED SILICA SODIUM LAURYL SULFATE SODIUM PHOSPHATE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM SACCHARIN SODIUM TITANIUM DIOXIDE SORBITOL SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202 MADE IN MEXICO"],"version":"9","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}