{"active_ingredient":["Drug Facts Active ingredient Stannous fluoride 0.454% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. do not swallow children under 12 yrs. of age: ask a dentist"],"effective_time":"20260108","id":"47e58bf6-e13b-346e-e063-6294a90a690c","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, sodium lauryl sulfate, sodium gluconate, carrageenan, flavor, sodium citrate, xanthan gum, zinc citrate, sodium saccharin, sodium hydroxide, stannous chloride, sucralose, titanium dioxide"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis"],"keep_out_of_reach_of_children":[""],"openfda":{"application_number":["M021"],"brand_name":["Crest Pro-health Gum Detoxify Deep Clean"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-756-85","69423-756-26","69423-756-37","69423-756-38","69423-756-28","69423-756-41","69423-756-42","69423-756-48","69423-756-96","69423-756-03","69423-756-06","69423-756-07","69423-756-01"],"product_ndc":["69423-756"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["47e58bf6-e13b-346e-e063-6294a90a690c"],"spl_set_id":["f498b727-c38c-1d67-e053-2995a90a0f11"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"],"upc":["0037000753490"]},"package_label_principal_display_panel":["Principal Display Panel - 24 g tube in carton CREST PRO-HEALTH FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS NET WT 0.85 OZ (24 g) GUM DETOXIFY NEUTRALIZES PLAQUE BACTERIA, EVEN AROUND THE GUMLINE, FOR 24 HOURS* DEEP CLEAN PREVENT HARMFUL OXIDANTS BY REVERSING GINGIVITIS artwork"],"purpose":["Purposes Anticavity, antigingivitis toothpaste"],"questions":["Questions? 1-800-594-4158"],"set_id":"f498b727-c38c-1d67-e053-2995a90a0f11","spl_product_data_elements":["Crest Pro-health Gum Detoxify Deep Clean Stannous fluoride STANNOUS CHLORIDE WATER HYDRATED SILICA CARRAGEENAN SODIUM GLUCONATE XANTHAN GUM ZINC CITRATE SODIUM LAURYL SULFATE SORBITOL SODIUM HYDROXIDE SACCHARIN SODIUM TITANIUM DIOXIDE STANNOUS FLUORIDE FLUORIDE ION SODIUM CITRATE SUCRALOSE"],"spl_unclassified_section":["DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"12","warnings":["Warning Keep out of reach of children under 12 yrs. of age . If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"warnings_and_cautions":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist this Crest is specially formulated to help prevent staining see your dentist regularly"]}