{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.16% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e5cb38-b55d-9cfb-e063-6394a90a8fda","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, sodium hydroxide, flavor, cellulose gum, sodium saccharin, carbomer, sucralose, polysorbate 80, titanium dioxide, mica"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Advanced Glamorous White"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-768-38","69423-768-77","69423-768-39","69423-768-93","69423-768-23","69423-768-66","69423-768-03"],"product_ndc":["69423-768"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e5cb38-b55d-9cfb-e063-6394a90a8fda"],"spl_set_id":["f5b18988-68c7-40f9-e053-2995a90a22bc"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 93 g Tube Carton CREST 3D WHITE ADVANCED GLAMOROUS WHITE DAILY WHITENING UPKEEP WHITER TEETH IN 5 DAYS NET WT 3.3 OZ (92 g) FLUORIDE ANTICAVITY TOOTHPASTE ENAMEL SAFE Artwork"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"f5b18988-68c7-40f9-e053-2995a90a22bc","spl_product_data_elements":["Crest 3D White Advanced Glamorous White Sodium Fluoride MICA TITANIUM DIOXIDE SODIUM SACCHARIN CELLULOSE GUM CARBOMER SUCRALOSE DISODIUM PYROPHOSPHATE SORBITOL HYDRATED SILICA SODIUM LAURYL SULFATE SODIUM HYDROXIDE POLYSORBATE 80 WATER SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"12","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}