{"active_ingredient":["Active ingredient Adapalene USP 0.1% (retinoid)* *read consumer information leaflet"],"do_not_use":["Do not use on damaged skin (cuts, abrasions eczema, sunburn) if you are allergic to adapalene or any of the ingredients in this product"],"dosage_and_administration":["Directions Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne in on the face, apply the product to the entire face. do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age : ask a doctor"],"effective_time":"20260111","id":"4821e693-2293-b60e-e063-6294a90a7d86","inactive_ingredient":["Inactive ingredients carbomer homopolymer, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide"],"indications_and_usage":["Use for the treatment of acne"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["ANDA091314"],"brand_name":["Curist Acne Relief"],"generic_name":["ADAPALENE"],"is_original_packager":[true],"manufacturer_name":["Little Pharma, Inc."],"nui":["N0000175607","M0018962"],"package_ndc":["72559-015-13","72559-015-17"],"pharm_class_cs":["Retinoids [CS]"],"pharm_class_epc":["Retinoid [EPC]"],"product_ndc":["72559-015"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["307731"],"spl_id":["4821e693-2293-b60e-e063-6294a90a7d86"],"spl_set_id":["e6380880-5299-0826-e053-2a95a90a1942"],"substance_name":["ADAPALENE"],"unii":["1L4806J2QF"],"upc":["0372559015133"]},"package_label_principal_display_panel":["curist Acne Relief Adapalene Gel, 0.1% Acne Teatment Once Daily Topical Retinoid* Fragrance Free Oil Free NET WT 1.6 oz (45 g) AdapaleneGel-45G Final"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a doctor before use"],"purpose":["Purpose Acne treatment"],"questions":["Questions? Call 1 (888) 721-7115"],"set_id":"e6380880-5299-0826-e053-2a95a90a1942","spl_product_data_elements":["Curist Acne Relief Adapalene CARBOMER HOMOPOLYMER TYPE C (ALLYL PENTAERYTHRITOL CROSSLINKED) EDETATE DISODIUM METHYLPARABEN POLOXAMER 182 PROPYLENE GLYCOL WATER SODIUM HYDROXIDE ADAPALENE ADAPALENE"],"spl_unclassified_section":["Drug Facts","*Read carton and enclosed consumer information leaflet before using this product. Keep this carton and consumer information leaflet.The contain important information. Distributed by: Little Pharma, Inc. New York, NY 10023 | Made in India"],"stop_use":["Stop use and ask a doctor if you become pregnant, or planning to become pregnant while using this product you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath) irritation become severe you see no improvement after 3 months of once daily use"],"storage_and_handling":["Other information store at room temperature 68º to 77ºF protect from freezing"],"version":"3","warnings":["Warnings For external use only Do not use on damaged skin (cuts, abrasions eczema, sunburn) if you are allergic to adapalene or any of the ingredients in this product If pregnant or breast-feeding, ask a doctor before use When using this product limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors do not wax to remove hair in areas where the product has been applied during the early weeks of use, your acne may appear to worsen before it improves (this is normal); continue using as directed, unless you get irritation that become severe irritation (redness, itching, dryness, burning) is more likely to occur: in the first few weeks of use if using more than one topical acne medication at a time but irritation usually lessens with continued use of this product it may take up to 3 months of once daily use to see result avoid product contact eyes, lips, and month. If contact occurs immediately flush the area with water. wash hands after use Stop use and ask a doctor if you become pregnant, or planning to become pregnant while using this product you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath) irritation become severe you see no improvement after 3 months of once daily use Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors do not wax to remove hair in areas where the product has been applied during the early weeks of use, your acne may appear to worsen before it improves (this is normal); continue using as directed, unless you get irritation that become severe irritation (redness, itching, dryness, burning) is more likely to occur: in the first few weeks of use if using more than one topical acne medication at a time but irritation usually lessens with continued use of this product it may take up to 3 months of once daily use to see result avoid product contact eyes, lips, and month. If contact occurs immediately flush the area with water. wash hands after use"]}