{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260212","id":"4aa60484-78be-875c-e063-6294a90ab84f","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, sodium lauryl sulfate, flavor, trisodium phosphate, cellulose gum, sodium saccharin, sodium phosphate, carbomer, titanium dioxide"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Fresh and White"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-868-02","37000-868-06","37000-868-24","37000-868-57"],"product_ndc":["37000-868"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["4aa60484-78be-875c-e063-6294a90ab84f"],"spl_set_id":["8693fa6d-e9c9-4cb7-bd3d-8ad87a7bb77e"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 68 g Tube Carton CLEANS & WHITENS TEETH* Crest ® FLUORIDE ANTICAVITY TOOTHPASTE NET WT 2.4 OZ (68 g) FRESH AND WHITE Peppermint GLEEM ™ Paste 868"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"8693fa6d-e9c9-4cb7-bd3d-8ad87a7bb77e","spl_product_data_elements":["Crest Fresh and White Sodium Fluoride WATER HYDRATED SILICA SODIUM LAURYL SULFATE SODIUM PHOSPHATE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM SACCHARIN SODIUM TITANIUM DIOXIDE SODIUM FLUORIDE FLUORIDE ION SORBITOL"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"12","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}