{"active_ingredient":["Active ingredients Sodium Fluoride 0.22%(0.1 w/v Fluoride ion) Purpose Anticavity toothpaste"],"dosage_and_administration":["Directions For Use: Wet toothbrush and dip into powder until brush is fully covered. Brush teeth and gum line for tleast 30 seconds, rinse and spit out thoroughly do not swallow . supervise children as necessary until capable of useing without supervision instruct children under 12 years of age in good brushing and rinsing habits (to minimize swallowing). Adults and children 6 years of age and older:Brush teeth thoroughly,preferably after each meal or at least twice a day,or as directed by a dentist or a physician. Children under 6 years of age:do not use unless directed by a doctor or dentist."],"effective_time":"20260310","id":"4cb875fc-cd0c-7d69-e063-6294a90ab865","inactive_ingredient":["INACTIVE INGREDIENT Calcium carbonate, Silica, Sodium Lauryl Sulfate, Flavor, Sodium Saccharin, Methylparaben, Propylparaben"],"indications_and_usage":["Uses aids in the prevention of dental cavities."],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 years of age."],"openfda":{"application_number":["M021"],"brand_name":["Amerfresh Toothpowder"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Yangzhou ONE & ONLY Personal Care Products Co., LTD"],"package_ndc":["85162-007-01","85162-007-02"],"product_ndc":["85162-007"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["245598"],"spl_id":["4cb875fc-cd0c-7d69-e063-6294a90ab865"],"spl_set_id":["1cacf93e-aa60-4717-87ab-0568a701a4f3"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["Label"],"purpose":["Purpose Anticavity toothpaste"],"set_id":"1cacf93e-aa60-4717-87ab-0568a701a4f3","spl_product_data_elements":["Amerfresh Toothpowder Sodium Fluoride SODIUM SACCHARIN CALCIUM CARBONATE HYDRATED SILICA SODIUM LAURYL SULFATE SODIUM FLUORIDE FLUORIDE ION METHYLPARABEN PROPYLPARABEN"],"version":"2","warnings":["Warnings Keep out of the reach of children under 6 years of age. If more than used for brushing is accidently swallowed,get medical help or contact a Poison Control Center immediately. Keep out of reach of children under 6 years of age."]}