{"active_ingredient":["Drug Facts Active ingredients (in each caplet) Acetaminophen 500 mg Caffeine 60 mg Pyrilamine maleate 15 mg"],"ask_doctor":["Ask a doctor before use if you have liver disease glaucoma difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis"],"ask_doctor_or_pharmacist":["Ask a doctoror pharmacist before use if you are taking the blood thinning drug warfarin takin sedatives or tranquilizers"],"do_not_use":["Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist if you have ever had an allergic reaction to this product or any of its ingredients"],"dosage_and_administration":["Directions do not exceed recommended dosage Adults and children 12 years and over: take 2 caplets with water every 6 hours as needed do not exceed 6 caplets per day Children under 12 years: do not use"],"effective_time":"20260311","id":"4cc4b39a-39d6-a2bb-e063-6394a90a2e95","inactive_ingredient":["Inactive ingredients colloidal silicon dioxide, hydroxy propyl methyl cellulose, microcrystalline cellulose, polyethylene glycol, corn starch, povidone, sodium starch glycolate, stearic acid, talc, titanium dioxide, lactose, purified water"],"indications_and_usage":["Uses for the temporary relief of these symptoms associated with menstrual periods: cramps bloating water-weight gain headache backache muscle aches fatigue"],"keep_out_of_reach_of_children":["Keep out of reach of children In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{"application_number":["M013"],"brand_name":["Buscapina"],"generic_name":["ACETAMINOPHEN, CAFFEINE, PYRILAMINE MALEATE"],"is_original_packager":[true],"manufacturer_name":["OPMX LLC"],"nui":["N0000175739","N0000175729","N0000175790","M0023046"],"package_ndc":["69729-818-50"],"pharm_class_cs":["Xanthines [CS]"],"pharm_class_epc":["Central Nervous System Stimulant [EPC]","Methylxanthine [EPC]"],"pharm_class_pe":["Central Nervous System Stimulation [PE]"],"product_ndc":["69729-818"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1597298"],"spl_id":["4cc4b39a-39d6-a2bb-e063-6394a90a2e95"],"spl_set_id":["4cc4b39a-39d5-a2bb-e063-6394a90a2e95"],"substance_name":["PYRILAMINE MALEATE","ACETAMINOPHEN","CAFFEINE"],"unii":["R35D29L3ZA","362O9ITL9D","3G6A5W338E"],"upc":["0810053180570","0810053181386"]},"other_safety_information":["Other information Store between 15-30°C(59-86°F) avoid excessive heat & humidity TAMPER EVIDENT: DO NOT USE IF PACKAGE IS OPENED OR IF BLISTER UNIT IS TORN, BROKEN OR SHOWS ANY SIGN OF TAMPERING"],"package_label_principal_display_panel":["NDC 69729-818-50 Buscapina Pain Reliever Alivia los Síntomas Cramps/Cólicos Bloating/ Hinchazón Fatigue/Fatiga Headache/Dolor de Cabeza Backache/Dolor de espalda Acetaminophen 500 mg Pain Reliever Caffeine 60 mg Diuretic Pyrilamine Maleate 15 mg Antihistamine 100 Caplets 50 packs of 2 Caplets pdp pouch"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding ask a health professional before use."],"purpose":["Purpose Pain reliever Diuretic Anthistamine"],"questions":["Questions or comments? Call toll free 619-600-5632 Monday through Friday 9AM - 5PM EST"],"set_id":"4cc4b39a-39d5-a2bb-e063-6394a90a2e95","spl_product_data_elements":["Buscapina Acetaminophen, Caffeine, Pyrilamine maleate SILICON DIOXIDE MICROCRYSTALLINE CELLULOSE PYRILAMINE MALEATE PYRILAMINE ACETAMINOPHEN ACETAMINOPHEN POLYETHYLENE GLYCOL, UNSPECIFIED POVIDONE K30 SODIUM STARCH GLYCOLATE TYPE A CAFFEINE CAFFEINE HYDROXYPROPYL METHYLCELLULOSE STARCH, CORN STEARIC ACID TALC TITANIUM DIOXIDE LACTOSE WATER V1"],"spl_unclassified_section":["Licensed by: Gute Besserung Hauser LLC Exclusively distributed by: OPMX Chula Vista, CA 91910 Phone: 619-600-5632"],"stop_use":["Stop use and ask a doctor if new symptoms appear redness or swelling is present pain gets worse or lasts for more than 10 days fever gets worse or lasts for more than 3 days"],"version":"1","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 6 caplets in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: skin reddening blisters rash hives facial swelling asthma (wheezing) shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have liver disease glaucoma difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis Ask a doctoror pharmacist before use if you are taking the blood thinning drug warfarin takin sedatives or tranquilizers When using this product you may get drowsy avoid alcoholic drinks excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery limit the use of caffeine-containing medications, foods, or beverages because too much caffeine may cause nervousness, irritability sleeplessness, and, occasionally rapid heartbeat. The recommended dose of this product contains about as much caffeine as a cup of coffee. Stop use and ask a doctor if new symptoms appear redness or swelling is present pain gets worse or lasts for more than 10 days fever gets worse or lasts for more than 3 days If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"when_using":["When using this product you may get drowsy avoid alcoholic drinks excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery limit the use of caffeine-containing medications, foods, or beverages because too much caffeine may cause nervousness, irritability sleeplessness, and, occasionally rapid heartbeat. The recommended dose of this product contains about as much caffeine as a cup of coffee."]}