{"do_not_use":["Do not use on damaged or broken skin"],"dosage_and_administration":["Directions apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every 2 hours Sun Protection Measures. Spending time in the sun increase your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: • limit time in the sun, especially from 10 a.m. - 2 p.m. • wear long-sleeved shirts, pants, hats, and sunglasses children under 6 months: ask a doctor"],"effective_time":"20260401","id":"4e6b948e-d0a9-327a-e063-6294a90ab6f6","inactive_ingredient":["Water･Glycerin･Dipropylene Glycol･Dimethicone･Alcohol Denat.･C12-15 Alkyl Benzoate･Behenyl Alcohol･Butylene Glycol･Silica･Diphenylsiloxy Phenyl Trimethicone･Isododecane･Sorbitol･Stearyl Alcohol･Phytosteryl Macadamiate･Erythritol･Tocopheryl Acetate･PEG/PPG-14/7 Dimethyl Ether･PEG/PPG-17/4 Dimethyl Ether･Xanthan Gum･Caffeine･Sapindus Mukorossi Peel Extract･Angelica Keiskei Leaf/Stem Extract･Camellia Sinensis Leaf Extract･Citrus Junos Seed Extract･Ziziphus Jujuba Fruit Extract･Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract･Potentilla Erecta Root Extract･Polyquaternium-51･Saccharina Angustata/Undaria Pinnatifida Extract･Chlorella Vulgaris Extract･Beheneth-20･Batyl Alcohol･Alcohol･Succinoglycan･Trisodium EDTA･Sodium Citrate･Sodium Metaphosphate･BHT･Citric Acid･Sodium Metabisulfite･PPG-3 Dipivalate･Tocopherol･Phenoxyethanol･Fragrance･Iron Oxides･"],"indications_and_usage":["Uses helps prevent sunburn"],"keep_out_of_reach_of_children":["Keep out of reach of children. If product is swallowed, get medical help or contact Poison Control Center right away"],"openfda":{"application_number":["M020"],"brand_name":["SHISEIDO BENEFIANCE WRINKLE SMOOTHING DAY"],"generic_name":["AVOBENZONE, HOMOSALATE, OCTISALATE, AND OCTOCRYLENE"],"is_original_packager":[true],"manufacturer_name":["Shiseido Americas Corporation"],"package_ndc":["58411-017-50"],"product_ndc":["58411-017"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"spl_id":["4e6b948e-d0a9-327a-e063-6294a90ab6f6"],"spl_set_id":["cad3a446-36a8-4146-81b5-1cc8d65abf14"],"substance_name":["AVOBENZONE","HOMOSALATE","OCTISALATE","OCTOCRYLENE"],"unii":["G63QQF2NOX","V06SV4M95S","4X49Y0596W","5A68WGF6WM"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 50 mL Jar Carton SHISEIDO GINZA TOKYO BENEFIANCE Wrinkle Smoothing Day Cream BROAD SPECTRUM SPF 25 SUNSCREEN Target wrinkles 50mL NET. WT. 1.8 OZ. smoothing cream"],"purpose":["Active Ingredients Purpose Avobenzone 2.5% Sunscreen Homosalate 4.5% Sunscreen Octisalate 4.5% Sunscreen Octocrylene 5.0% Sunscreen"],"purpose_table":["<table width=\"100%\"><caption/><tbody><tr><td><content styleCode=\"italics\"><content styleCode=\"bold\"> Active Ingredients</content></content></td><td><content styleCode=\"italics\"><content styleCode=\"bold\"> Purpose</content></content></td></tr><tr><td>Avobenzone 2.5%</td><td>Sunscreen </td></tr><tr><td>Homosalate 4.5% </td><td>Sunscreen </td></tr><tr><td>Octisalate 4.5% </td><td>Sunscreen </td></tr><tr><td>Octocrylene 5.0% </td><td>Sunscreen </td></tr></tbody></table>"],"questions":["Questions or Comments? Call toll free 1-800-906-7503"],"set_id":"cad3a446-36a8-4146-81b5-1cc8d65abf14","spl_product_data_elements":["SHISEIDO BENEFIANCE WRINKLE SMOOTHING DAY Avobenzone, Homosalate, Octisalate, and Octocrylene WATER GLYCERIN DIPROPYLENE GLYCOL DIMETHICONE ALCOHOL C12-15 ALKYL BENZOATE BEHENYL ALCOHOL BUTYLENE GLYCOL SILICA DIPHENYLSILOXY PHENYL TRIMETHICONE ISODODECANE SORBITOL STEARYL ALCOHOL PHYTOSTERYL MACADAMIATE ERYTHRITOL .ALPHA.-TOCOPHEROL ACETATE PEG/PPG-14/7 DIMETHYL ETHER PEG/PPG-17/4 DIMETHYL ETHER XANTHAN GUM CAFFEINE SAPINDUS MUKOROSSI FRUIT RIND ANGELICA KEISKEI WHOLE CAMELLIA SINENSIS LEAF CITRUS JUNOS SEED ZIZIPHUS JUJUBA WHOLE POTENTILLA ERECTA ROOT POLYQUATERNIUM-51 (2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE/N-BUTYL METHACRYLATE; 3:7) CHLORELLA VULGARIS BEHENETH-20 BATYL ALCOHOL SUCCINOGLYCAN (AGROBACTERIUM TUMEFACIENS) TRISODIUM EDTA SODIUM CITRATE SODIUM METAPHOSPHATE BUTYLATED HYDROXYTOLUENE CITRIC ACID SODIUM METABISULFITE TOCOPHEROL PHENOXYETHANOL FERRIC OXIDE RED AVOBENZONE AVOBENZONE HOMOSALATE HOMOSALATE OCTISALATE ETHYLHEXYL SALICYLATE OCTOCRYLENE OCTOCRYLENE"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if rash occurs"],"storage_and_handling":["Other information protect this product in this container from excessive heat and direct sun."],"version":"2","warnings":["Warnings For external use only"],"when_using":["When using this product keep out of eyes. Rinse with water to remove"]}