{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260407","id":"4ee0534f-21b4-92f4-e063-6394a90a98a8","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, sodium hydroxide, flavor, cellulose gum, sodium saccharin, carbomer, charcoal powder, polysorbate 80, mica, titanium dioxide"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Advanced Charcoal"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-767-28","69423-767-38","69423-767-76","69423-767-27","69423-767-29","69423-767-39","69423-767-24","69423-767-33","69423-767-03","69423-767-66","69423-767-93"],"product_ndc":["69423-767"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["4ee0534f-21b4-92f4-e063-6394a90a98a8"],"spl_set_id":["f4eb8111-53da-17ae-e053-2a95a90a1127"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 107 g Tube Carton Crest 3D WHITE NET WT 3.8 OZ (107 g) FLUORIDE ANTICAVITY TOOTHPASTE ENAMEL SAFE WHIENENING ADVANCED CHARCOAL REMOVES 90% MORE SUFACE STAINS* STARTS WHITENING AFTER 1 BRUSH LABEL"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"f4eb8111-53da-17ae-e053-2a95a90a1127","spl_product_data_elements":["Crest 3D White Advanced Charcoal Sodium Fluoride SODIUM HYDROXIDE POLYSORBATE 80 SODIUM ACID PYROPHOSPHATE SORBITOL CARBOXYMETHYLCELLULOSE SODIUM HYDRATED SILICA WATER SODIUM LAURYL SULFATE SACCHARIN SODIUM MICA TITANIUM DIOXIDE CARBOXYPOLYMETHYLENE SODIUM FLUORIDE FLUORIDE ION ACTIVATED CHARCOAL"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"12","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}