{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260407","id":"4ee301a4-a350-8e4c-e063-6394a90a2263","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, cellulose gum, sodium saccharin, carbomer, polysorbate 80, mica, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Arctic Fresh"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-875-03","37000-875-04","37000-875-06","37000-875-07","37000-875-08","37000-875-10","37000-875-42","37000-875-15","37000-875-99","37000-875-77","37000-875-30","37000-875-41","37000-875-54","37000-875-27","37000-875-50","37000-875-38","37000-875-02","37000-875-33","37000-875-56","37000-875-93","37000-875-49","37000-875-29","37000-875-24","37000-875-63","37000-875-64","37000-875-13"],"product_ndc":["37000-875"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL","ORAL"],"rxcui":["891775"],"spl_id":["4ee301a4-a350-8e4c-e063-6394a90a2263"],"spl_set_id":["fa08a877-b9e5-4eba-b832-3a28f4f3f83c"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 68 g Tube Carton CREST 3D WHITE ADVANCED ARCTIC FRESH DAILY WHITENING UPKEEP WHITER TEETH IN 5 DAYS NET WT 2.5 OZ (68g) fluoride anticavity toothpaste enamel safe Artwork"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"fa08a877-b9e5-4eba-b832-3a28f4f3f83c","spl_product_data_elements":["Crest 3D White Arctic Fresh Sodium Fluoride MICA TITANIUM DIOXIDE FD&C BLUE NO. 1 SODIUM FLUORIDE FLUORIDE ION CELLULOSE GUM CARBOXYPOLYMETHYLENE POLYSORBATE 80 WATER SORBITOL HYDRATED SILICA SODIUM ACID PYROPHOSPHATE SODIUM LAURYL SULFATE SODIUM HYDROXIDE SACCHARIN SODIUM"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"22","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}