{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260409","id":"4f08260b-c544-87ed-e063-6394a90a3639","inactive_ingredient":["Inactive ingredients water, hydrated silica, sorbitol, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, xanthan gum, sodium saccharin, poloxamer 407, cocamidopropyl betaine, polysorbate 80, mica, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Advanced Arctic Fresh with Stain-Blasting Foam"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["84126-628-24","84126-628-33","84126-628-49","84126-628-05","84126-628-06","84126-628-04"],"product_ndc":["84126-628"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["4f08260b-c544-87ed-e063-6394a90a3639"],"spl_set_id":["4ef4146d-6281-fe66-e063-6394a90a32c3"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"],"upc":["0030772125526"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 68 g Tube Carton CREST 3D WHITE ADVANCED ARCTIC FRESH WITH STAIN-BLASTING FOAM Whiter Teeth in 5 DAYS new wt 2.4 OZ (68 g) fluoride anticavity toothpaste enamel safe label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"4ef4146d-6281-fe66-e063-6394a90a32c3","spl_product_data_elements":["Crest 3D White Advanced Arctic Fresh with Stain-Blasting Foam Sodium Fluoride XANTHAN GUM POLOXAMER 407 SODIUM LAURYL SULFATE FD&C BLUE NO. 1 POLYSORBATE 80 SORBITOL WATER TITANIUM DIOXIDE HYDRATED SILICA SACCHARIN SODIUM MICA COCAMIDOPROPYL BETAINE DISODIUM PYROPHOSPHATE SODIUM FLUORIDE FLUORIDE ION SODIUM HYDROXIDE"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"3","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}