{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260409","id":"4f087771-a0cc-bc81-e063-6394a90a302d","inactive_ingredient":["Inactive ingredients water, hydrated silica, sorbitol, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, xanthan gum, sodium saccharin, poloxamer 407, cocamidopropyl betaine, polysorbate 80, mica, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Advanced Luminous Mint Daily Whitening Upkeep"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["84126-633-37","84126-633-43"],"product_ndc":["84126-633"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["4f087771-a0cc-bc81-e063-6394a90a302d"],"spl_set_id":["4f0876d9-41c9-d891-e063-6394a90a1cbd"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 104 g Tube Carton CREST 3D WHITE ADVANCED LUMINOUS MINT DAILY WHITENING UPKEEP Whiter Teeth in 5 DAYS new wt 3.7 oz (104 g) fluoride anticavity toothpaste enamel safe label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"4f0876d9-41c9-d891-e063-6394a90a1cbd","spl_product_data_elements":["Crest 3D White Advanced Luminous Mint Daily Whitening Upkeep Sodium Fluoride XANTHAN GUM POLOXAMER 407 DISODIUM PYROPHOSPHATE SODIUM LAURYL SULFATE SODIUM HYDROXIDE FD&C BLUE NO. 1 POLYSORBATE 80 SORBITOL WATER TITANIUM DIOXIDE HYDRATED SILICA SACCHARIN SODIUM MICA COCAMIDOPROPYL BETAINE SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"1","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}