{"active_ingredient":["Estriol 5 g 50000 mcg Estriol 5 g 50000 mcg"],"dosage_and_administration":["DOSAGE AND USE Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or use as directed by your physician. Each pump is 5 g of Estriol"],"effective_time":"20260411","id":"4f378a16-c63d-bc64-e063-6294a90a0d2d","inactive_ingredient":["INACTIVE INGREDIENTS Purified Water, Vegetable Glycerin, (Kosher Source), Micronized Estriol USP, Caprylic/Capric Triglyceride, Aloe Vera Gel, Stearic Acid, MSM (Methylsulfonylmethane), Isopropyl Palmitate, Herbs & Blend of Essential Oils (Natural Preservative), Olive Oil, Coconut Oil, Stearyl Alcohol, Shea Butter, Carbopol® Ultrez 10,, Sunflower Lecithin"],"indications_and_usage":["Indication and Usage Section USES: This is a topical cream that contains bio-identical estriol derived from wild yam. When applied to the skin it can help balance your hormones and provide temporary relief from menopausal symptoms such as hot flashes. DIRECTIONS: Apply once or twice a day. Massage into inner arms, thighs, chest or apply to inner forearm and rub arms together or use as directed by your Physician."],"keep_out_of_reach_of_children":["KEEP OUT OF REACH OF CHILDREN KEEP OUT OF REACH OF CHILDREN"],"openfda":{},"package_label_principal_display_panel":["Estriol Label Estriol EStriol %g 5000 mcg"],"package_label_principal_display_panel_table":["<table border=\"0\" width=\"100%\"><caption>Estriol</caption><tbody><tr><td><renderMultiMedia referencedObject=\"img_4fbd636b-35b2-0168-e063-6394a90a4cb1\"/></td><td/><td/></tr><tr><td/><td/><td/></tr><tr><td/><td/><td/></tr><tr><td/><td/><td/></tr></tbody></table>"],"pregnancy_or_breast_feeding":["PREGNANT OR BREASTFEEDING If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product."],"purpose":["PURPOSE This is a topical cream that contains bio-identical micronized USP Estriol derived from wild yam, blended moisturizing MSN, Shea Butter, Olive Oil,and Coconut Oil. When applied topically to the skin, it may help to balance your hormones and provide support for perimenopause and menopause"],"questions":["QUESTIONS Contact support@wiseessentials.com www.wiseessentials.com"],"references":["REFERENCE SECTION Medline Plus. Click here https://vsearch.nlm.nih.gov/ Medline Plus, Clinical Trials, PubMed, Biochemical Data Summary https://clinicaltrials.gov/search?term=ESTRIOL https://go.drugbank.com/drugs/DB04573 Report Adverse Events click here https://www.accessdata.fda.gov/scripts/medwatch/ FDA Safety Recalls Click here https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts Presence in Breast Milk Click here https://www.ncbi.nlm.nih.gov/books/NBK501345/ Report Adverse Events click here https://www.accessdata.fda.gov/scripts/medwatch/</p> <p></p> <p>FDA Safety Recalls Click here https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts</p> <p></p> <p>Presence in Breast Milk Click here https://www.ncbi.nlm.nih.gov/books/NBK501345/</p>"],"set_id":"4f378a16-c63c-bc64-e063-6294a90a0d2d","spl_product_data_elements":["Estriol 5000 mcg 5 g Estriol 5000 mcg 5g STEARIC ACID GLYCERIN ISOPROPYL PALMITATE ESTRIOL ESTRIOL COCONUT OIL SHEA BUTTER ALOE VERA LEAF SODIUM BICARBONATE OLIVE OIL LECITHIN, SUNFLOWER ALLANTOIN"],"version":"1","warnings":["WARNINGS If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product. Discontinue use if skin irritation or red skin develops, and consult a Physician. California Prop 65 Law requires this statement: This product contains progesterone, a chemical known only to the State of California to cause cancer. Cease using this product and seek medical attention if skin irritation or other negative reactions occur."]}