{"active_ingredient":["Active ingredient Cetylpyridinium chloride 0.07%"],"ask_doctor":["Ask a dentist if symptoms persist or condition worsens after regular use."],"dosage_and_administration":["Directions use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use adults and children 6 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day do not swallow children 6 years to under 12 years of age: supervise use children under 6 years of age: do not use"],"effective_time":"20260414","id":"4f6ec197-7cf1-459a-e063-6294a90aee7c","inactive_ingredient":["Inactive ingredients water, glycerin, flavor, poloxamer 407, sodium benzoate, sodium saccharin, sucralose, benzoic acid, red 33, blue 1, green 3"],"indications_and_usage":["Uses helps prevent and reduce plaque and gingivitis helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M022"],"brand_name":["Crest Pro-Health Nightly Bacteria Shield"],"generic_name":["CETYLPYRIDINIUM CHLORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["84126-650-01"],"product_ndc":["84126-650"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1100924","1251371"],"spl_id":["4f6ec197-7cf1-459a-e063-6294a90aee7c"],"spl_set_id":["4f6ec1e0-c6b5-226f-e063-6294a90a8f14"],"substance_name":["CETYLPYRIDINIUM CHLORIDE"],"unii":["D9OM4SK49P"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 1 L Bottle Label ALCOHOL FREE Crest PRO-HEALTH CPC ANTIGINGIVITIS/ANTIPLAQUE ORAL RINSE NIGHTLY BACTERIA SHIELD 12-Hour Anti-Bacterial for Overnight Protection SOOTHING MINT 1 L (33.8 FL OZ) label"],"purpose":["Purpose Antigingivitis/antiplaque"],"questions":["Questions? 1–800–285–9139"],"set_id":"4f6ec1e0-c6b5-226f-e063-6294a90a8f14","spl_product_data_elements":["Crest Pro-Health Nightly Bacteria Shield Cetylpyridinium chloride GREEN 3 SODIUM BENZOATE SUCRALOSE BENZOIC ACID FD&C BLUE NO. 1 POLOXAMER 407 WATER GLYCERIN SACCHARIN SODIUM CETYLPYRIDINIUM CHLORIDE CETYLPYRIDINIUM RED 33"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"1","warnings":["Warnings Ask a dentist if symptoms persist or condition worsens after regular use. Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}