{"dosage_and_administration":["Directions: Use as Directed This prescription dentifrice is recommended for adults and pediatric patients six years and older. • Apply a thin ribbon of PRO-SYS Professional along the length of the toothbrush no more than \"pea size\" total dose. Brush for two minutes. • After brushing: ADULTS-Expectorate; do not eat or drink for 30 minutes. CHILDREN SIX YEARS OF AGE OR OLDER-Expectorate and rinse mouth with water. • Use at bedtime in place of your regular toothpaste or as directed by your dental professional."],"effective_time":"20251201","id":"500d975b-b5ef-fc25-e063-6294a90a8377","inactive_ingredient":["Inactive Ingredients Sorbitol, Hydrated Silica, Water, Glycerin, PEG-12, Titanium Dioxide, Cocamidopropyl Betaine, Flavor, Cellulose Gum, Xylitol, Sodium Benzoate, Disodium Phosphate, Sodium Saccharin"],"indications_and_usage":["Indications and Usage PRO-SYS Professional is a self-applied dentrifice for prevention of tooth decay, orthodontic decalcification and hypersensitivity."],"openfda":{"brand_name":["PRO-SYS"],"generic_name":["PROFESSIONAL SENSITIVITY, SLS FREE - MINT (5000 PPM)"],"is_original_packager":[true],"manufacturer_name":["Benco Dental"],"package_ndc":["66975-779-01"],"product_ndc":["66975-779"],"product_type":["HUMAN PRESCRIPTION DRUG"],"route":["DENTAL"],"rxcui":["637365"],"spl_id":["500d975b-b5ef-fc25-e063-6294a90a8377"],"spl_set_id":["4e4761d7-f1ab-aae4-e063-6294a90a214c"],"substance_name":["SODIUM FLUORIDE","POTASSIUM NITRATE"],"unii":["8ZYQ1474W7","RU45X2JN0Z"]},"package_label_principal_display_panel":["Principal Display Panel PRO-SYS® PROFESSIONAL ANTI-CAVITY FLUORIDE TOOTHPASTE RX ONLY 5000 PPM 1.1% SODIUM FLUORIDE 5% POTASSIUM NITRATE SENSITIVE MINT, 4 OZ. (113G) SODIUM LAURYL SULFATE FREE BENCO DENTAL Tube Box"],"set_id":"4e4761d7-f1ab-aae4-e063-6294a90a214c","spl_product_data_elements":["PRO-SYS Professional Sensitivity, SLS Free - Mint (5000 ppm) SODIUM FLUORIDE FLUORIDE ION XYLITOL SODIUM BENZOATE DISODIUM PHOSPHATE SODIUM SACCHARIN POTASSIUM NITRATE NITRATE ION HYDRATED SILICA TITANIUM DIOXIDE SORBITOL COCAMIDOPROPYL BETAINE GLYCERIN PEG-12 CELLULOSE GUM WATER"],"version":"2","warnings":["Warnings • Do not swallow • For topical use only • As with all medications, keep out of reach of children"]}