{"dosage_and_administration":["adults and children 2 years of age and older: Brush teeth thoroughly for at least 2 minute twice a day (morning and evening) or as recommended by a dentist or doctor. Do not swallow. Spit out after brushing. children 2 to 6 years of age: Use a pea-sized amount and supervise brushing. Instruct in good brushing and rinsing habits children under 2 years of age: Consult a dentist or doctor."],"effective_time":"20260423","id":"501dd0d9-3569-e560-e063-6394a90a856c","inactive_ingredient":["A Tube: glycerin, hydrated silica, propylene glycol, calcium sodium phosphosilicate, cocamidopropyl betaine, polyoxyl 15 hydroxystearate, PEG-20, aroma, hydroxyapatite, PVP, titanium dioxide, zinc citrate, sucralose, carboxymethyl chitosan, triacetin. B Tube: glycerin, water, hydrated silica,potassium nitrate, PEG-8, betaine, cocamidopropyl betaine, aroma, sodium lauryl sulfate, xanthan gum, sodium hydroxide, zinc citrate, strontium chloride hexahydrate, carbomer, arginine, sucralose, sodium carbonate, sodium bicarbonate, carboxymethyl chitosan, calcium aluminum borosilicate, tin oxide, titanium dioxide, blue 2."],"indications_and_usage":["Uses aids in the prevention of dental cavities. helps reduce and builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact."],"instructions_for_use":["①Please use it with electric dual toothpaste dispenser; ②Mount dual-formula toothpaste on the electric dispenser according to the instructions for use; ③For the first use, unscrew the cap and remove the sealing sticker on the opening of toothpaste tube; ④When the electric dispenser is turned on, press the Squeeze button to squeeze the toothpaste, release the button to stop squeezing, then apply the toothpaste to the toothbrush."],"keep_out_of_reach_of_children":["Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M022"],"brand_name":["3ECARE Dual formula WhiteningToothpaste Refill"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Hangzhou Namei Zhikang Technology Co., Ltd."],"package_ndc":["87514-002-01"],"product_ndc":["87514-002"],"product_type":["HUMAN OTC DRUG"],"route":["SUBGINGIVAL"],"spl_id":["501dd0d9-3569-e560-e063-6394a90a856c"],"spl_set_id":["501df1c7-4884-bb39-e063-6294a90aaf6a"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["1"],"purpose":["helps protect against cavities"],"recent_major_changes":["adults and children 2 years of age and older: Brush teeth thoroughly for at least 2 minute twice a day (morning and evening) or as recommended by a dentist or doctor. Do not swallow. Spit out after brushing. children 2 to 6 years of age: Use a pea-sized amount and supervise brushing. Instruct in good brushing and rinsing habits children under 2 years of age: Consult a dentist or doctor."],"set_id":"501df1c7-4884-bb39-e063-6294a90aaf6a","spl_product_data_elements":["3ECARE Dual formula WhiteningToothpaste Refill Sodium fluoride GLYCERIN SODIUM FLUORIDE FLUORIDE ION"],"version":"1","warnings":["It shall be used with electric dual toothpaste dispenser. Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}