{"active_ingredient":["Active ingredients (in each tablet) Acetaminophen 250mg Dextromethorphan hydrobromide 10 mg","Active ingredients (in each tablet) Acetaminophen 250 mg Chlorpheniramine maleate 2 mg Dextromethorphan hydrobromide 10 mg"],"ask_doctor":["Ask a doctor before use if you have ● liver disease ● cough that is accompanied by excessive phlegm (mucus) ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema ● a sodium-restricted diet","Ask a doctor before use if you have ● liver disease ● glaucoma ● cough that is accompanied by excessive phlegm (mucus) ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema ● difficulty in urination due to enlargement of the prostate gland ● a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin","Ask a doctor or pharmacist before use if you are • taking the blood thinning drug warfarin • taking sedatives or tranquilizers"],"do_not_use":["Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contatins acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age","Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions Directions ● do not take more than the recommended dose ● adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 10 tablets in 24 hours or as directed by a doctor. ● children under 12 years: do not use","Directions Directions ● do not take more than the recommended dose ● adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 10 tablets in 24 hours or as directed by a doctor. ● children under 12 years: do not use"],"effective_time":"20260427","id":"50762d7c-5efe-4f83-e063-6294a90abf7f","inactive_ingredient":["Inactive ingredients anhydrous citric acid, calcium silicate, dimethicone, flavors, magnesium stearate, maltodextrin, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose","Inactive ingredients anhydrous citric acid, calcium silicate, dimethicone, flavors, magnesium stearate, maltodextrin, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose"],"indications_and_usage":["Uses •temporarily relieves these symptoms due to a cold or flu:  • minor aches and pains  • headache • sore throat  • cough  • temporarily reduces fever","Uses Uses  • temporarily relieves these symptoms due to a cold or flu:  • minor aches and pains  • headache  • cough  • sore throat  • runny nose  • sneezing  • temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.","Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{"application_number":["M012"],"brand_name":["ALKA SELTZER COLD Cold and Flu Severe Day Night Fast Dissolve"],"generic_name":["ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE, DOXYLAMINE SUCCINATE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"package_ndc":["0280-8287-24"],"product_ndc":["0280-8287"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["2744312","2744315","2744508"],"spl_id":["50762d7c-5efe-4f83-e063-6294a90abf7f"],"spl_set_id":["50762d7c-5efd-4f83-e063-6294a90abf7f"],"upc":["0016500608141"]},"other_safety_information":["Other information Other information ● each tablet contains: potassium 80 mg; sodium 355 mg ● store between 20 o C to 25 o C (68 o F to 77 o F). Avoid excessive heat above 40 o C (104 o ​F).","Other information Other information ● each tablet contains: potassium 80 mg; sodium 355 mg ● store between 20 o C to 25 o C (68 o F to 77 o F). Avoid excessive heat above 40 o C (104 o ​F)."],"package_label_principal_display_panel":["Package Display Label PDP","PDP"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding , ask a health professional before use.","If pregnant or breast-feeding , ask a health professional before use."],"purpose":["Purposes Pain reliever/fever reducer Cough suppressant","Purposes Pain reliever/fever reducer Antihistamine Cough suppressant"],"questions":["Questions or comments ? 1-800-986-0369 (Mon – Fri 8AM – 8PM EST)","Questions or comments? Questions or comments? 1-800-986-0369 (Mon- Fri 8AM – 8PM EST)"],"set_id":"50762d7c-5efd-4f83-e063-6294a90abf7f","spl_product_data_elements":["ALKA SELTZER COLD Cold and Flu Severe Day Night Fast Dissolve Aspirin, Dextromethorphan hydrobromide, Phenylephrine bitartrate, Doxylamine succinate ALKA SELTZER COLD Cold and Flu Severe Fast Dissolve Day Acetaminophen, Dextromethorphan hydrobromide SUCRALOSE MAGNESIUM STEARATE ACETAMINOPHEN ACETAMINOPHEN SODIUM BICARBONATE CALCIUM SILICATE DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN MANNITOL POVIDONE ANHYDROUS CITRIC ACID DIMETHICONE MALTODEXTRIN POTASSIUM BICARBONATE ASC;CFD ALKA SELTZER COLD Cold Flu Severe Fast Dissolve chlorpheniramine maleate, acetaminophen, dextromethorphan hydrobromide CHLORPHENIRAMINE MALEATE CHLORPHENIRAMINE SUCRALOSE MAGNESIUM STEARATE ACETAMINOPHEN ACETAMINOPHEN SODIUM BICARBONATE CALCIUM SILICATE DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN MANNITOL POVIDONE ANHYDROUS CITRIC ACID DIMETHICONE MALTODEXTRIN POTASSIUM BICARBONATE SPECKLED Strawberry Honey ASP;CFS"],"spl_unclassified_section":["Alka-Seltzer Cold Cold & Flu Severe Day Fast Dissolve Effervescent Tablets","Drug Facts","Alka-Seltzer Cold Cold & Flu Severe Fast Dissolve Night Effervescent Tablets"],"stop_use":["Stop use and ask a doctor if ● pain or cough gets worse or lasts more than 7 days ● fever gets worse or lasts more than 3 days ● redness or swelling is present ● new symptoms occur ● cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.","Stop use and ask a doctor if ● pain or cough gets worse or lasts more than 7 days ● fever gets worse or lasts more than 3 days ● redness or swelling is present ● new symptoms occur ● cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition."],"version":"1","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take ● more than 10 tablets in 24 hours, which is the maximum daily amount for this product ● with other drugs containing acetaminophen ● 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: ● skin reddening ● blisters ● rash ● hives ● facial swelling ● asthma (wheezing) ● shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.","Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take ● more than 10 tablets in 24 hours, which is the maximum daily amount for this product ● with other drugs containing acetaminophen ● 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: ● skin reddening ● blisters ● rash ● hives ● facial swelling ● asthma (wheezing) ● shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children."],"when_using":["When using this product ● may cause marked drowsiness ● alcohol, sedatives, and tranquilizers may increase the drowsiness effect ● avoid alcoholic drinks ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children"]}