{"active_ingredient":["Active Ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in childrenunder 6 supervise children’s brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260428","id":"508a90bf-922a-2e4c-e063-6394a90a239a","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, sodium lauryl sulfate, trisodium phosphate, flavor, sodium phosphate, cellulose gum, carbomer, sodium saccharin, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect teeth and roots against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Cavity Protection Regular"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Procter & Gamble Manufactura, S. de R.L. de C.V."],"package_ndc":["58933-005-04","58933-005-11","58933-005-57","58933-005-82","58933-005-24","58933-005-85","58933-005-03"],"product_ndc":["58933-005"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["508a90bf-922a-2e4c-e063-6394a90a239a"],"spl_set_id":["852889b4-59ba-4592-b4fc-c0127a1ad075"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 161 g Tube Carton HELPS STOP CAVITIES BEFORE THEY START Crest ® CAVITY PROTECTION ADA Accepted American Dental Association® FLUORIDE ANTICAVITY TOOTHPASTE NET WT 5.7 OZ (161 g) Regular Paste Cavity protection"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"852889b4-59ba-4592-b4fc-c0127a1ad075","spl_product_data_elements":["Crest Cavity Protection Regular Sodium Fluoride SORBITOL WATER HYDRATED SILICA SODIUM LAURYL SULFATE SODIUM PHOSPHATE CARBOXYMETHYLCELLULOSE SODIUM SACCHARIN SODIUM TITANIUM DIOXIDE FD&C BLUE NO. 1 SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati, OH 45202"],"version":"15","warnings":["Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}