{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260624","id":"55003edd-9f63-d73e-e063-6394a90a05c6","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, alcohol (0.7%), xanthan gum, sodium saccharin, glycerin, poloxamer 407, cocamidopropyl betaine, sucralose, polysorbate 80, cetylpyridinium chloride, titanium dioxide, blue 1, yellow 5"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Premium Plus Active Foam Whitening scope"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["84126-660-72","84126-660-52","84126-660-03"],"product_ndc":["84126-660"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["55003edd-9f63-d73e-e063-6394a90a05c6"],"spl_set_id":["55004d9d-eda7-a285-e063-6294a90ad4ca"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 147 g Tube Carton Crest plus PREMIUM WITH FLIP CAP NET WT 5.2OZ (147 g) ANTICAVITY FLUORIDE TOOTHPASTE ACTIVE FOAM + WHITENING Long lasting fresh breath scope OUTLAST MINT WITH MOUTHWASH STRIPES label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"55004d9d-eda7-a285-e063-6294a90ad4ca","spl_product_data_elements":["Crest Premium Plus Active Foam Whitening scope Sodium Fluoride SUCRALOSE POLOXAMER 407 BLUE 1 POLYSORBATE 80 SODIUM SACCHARIN CETYLPYRIDINIUM CHLORIDE TITANIUM DIOXIDE SODIUM HYDROXIDE XANTHAN GUM SORBITOL WATER HYDRATED SILICA SODIUM LAURYL SULFATE ALCOHOL SODIUM FLUORIDE FLUORIDE ION COCAMIDOPROPYL BETAINE GLYCERIN YELLOW 5 DISODIUM PYROPHOSPHATE"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"1","warnings":["Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}