{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260625","id":"5514e0e6-2c16-67b7-e063-6294a90a3c55","inactive_ingredient":["Inactive ingredients water, hydrated silica, sorbitol, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, cellulose gum, sodium saccharin, polysorbate 80, mica, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Plus Extra Whitening"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["84126-666-54"],"product_ndc":["84126-666"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["5514e0e6-2c16-67b7-e063-6294a90a3c55"],"spl_set_id":["5514e09e-0a7d-93e6-e063-6294a90ae3f0"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 153 g Tube Carton Crest + Net WT 5.4 OZ (153 g) ANTICAVITY FLUORIDE TOOTHPASTE Whitens teeth & freshens breath EXTRA WHITENING CLEAN MINT label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"5514e09e-0a7d-93e6-e063-6294a90ae3f0","spl_product_data_elements":["Crest Plus Extra Whitening Sodium Fluoride MICA CELLULOSE GUM BLUE 1 POLYSORBATE 80 SODIUM SACCHARIN TITANIUM DIOXIDE SODIUM HYDROXIDE SORBITOL WATER HYDRATED SILICA SODIUM LAURYL SULFATE DISODIUM PYROPHOSPHATE SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"1","warnings":["Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}