{"active_ingredient":["Active ingredient Sodium fluoride 0.243%"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260601","id":"560980f2-39de-62f1-e063-6294a90aa419","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, sodium hydroxide, flavor, xanthan gum, sodium saccharin, poloxamer 407, cocamidopropyl betaine, sucralose, polysorbate 80, titanium dioxide"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest plus Tartar Protection Whitening"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["84126-670-24","84126-670-57","84126-670-82"],"product_ndc":["84126-670"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["560980f2-39de-62f1-e063-6294a90aa419"],"spl_set_id":["560980ea-749f-593d-e063-6394a90a1b9e"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 161 g Tube Carton Crest plus FLOURIDE ANTICAVITY TOOTHPASTE NET WT 5.7 OZ (161 g) TARTA PROTECTION WHITENING HELPS PREVENT TARTAR & WHITENS TEETH COOL MINT PASTE label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"recent_major_changes":[""],"set_id":"560980ea-749f-593d-e063-6394a90a1b9e","spl_product_data_elements":["Crest plus Tartar Protection Whitening Sodium Fluoride POLYSORBATE 80 POLOXAMER 407 SUCRALOSE COCAMIDOPROPYL BETAINE DISODIUM PYROPHOSPHATE HYDRATED SILICA WATER SORBITOL SODIUM HYDROXIDE SODIUM LAURYL SULFATE SACCHARIN SODIUM XANTHAN GUM TITANIUM DIOXIDE SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati, OH 45202"],"version":"1","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}