{"active_ingredient":["Active ingredients (in each tablet) Aspirin 325 mg (NSAID)* Chlorpheniramine maleate 2 mg Phenylephrine bitartrate 7.8 mg *nonsteroidal anti-inflammatory drug"],"ask_doctor":["Ask a doctor before use if ● stomach bleeding warning applies to you ● you have a history of stomach problems, such as heartburn ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ● you are taking a diuretic ● you have ● asthma ● diabetes ● thyroid disease ● glaucoma ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are · taking a prescription drug for diabetes, gout or arthritis · taking sedatives or tranquilizers"],"do_not_use":["Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions Directions ● adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 8 tablets in 24 hours or as directed by a doctor. ● children under 12 years: do not use"],"effective_time":"20260709","id":"562f6fa2-7c77-6376-e063-6294a90a437f","inactive_ingredient":["Inactive ingredients Inactive ingredients anhydrous citric acid, calcium silicate, dimethicone, FD&C red #40, FD&C yellow #6, flavor, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose"],"indications_and_usage":["Uses Uses · temporarily relieves these symptoms due to a cold: · minor aches and pains · headache · runny nose · nasal congestion · sinus congestion and pressure · sneezing · sore throat · temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M012"],"brand_name":["ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve Orange"],"generic_name":["ASPIRIN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE BITARTRATE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"nui":["N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["0280-8266-24","0280-8266-16"],"pharm_class_cs":["Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["0280-8266"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1536840"],"spl_id":["562f6fa2-7c77-6376-e063-6294a90a437f"],"spl_set_id":["50230cad-3d04-8882-e063-6294a90acf3c"],"substance_name":["PHENYLEPHRINE BITARTRATE","CHLORPHENIRAMINE MALEATE","ASPIRIN"],"unii":["27O3Q5ML57","V1Q0O9OJ9Z","R16CO5Y76E"],"upc":["0016500598855"]},"other_safety_information":["Other information Other information ● each tablet contains: potassium 80 mg; sodium 356 mg ● store between 20 o C to 25 o C (68 o F to 77 o F). Avoid excessive heat above 40 o C (104 o F)."],"package_label_principal_display_panel":["Carton 24 count PDP"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":["Purposes Pain reliever/fever reducer Antihistamine Nasal decongestant"],"questions":["Questions or Comments Questions or comments? 1-800-986-0369 (Mon – Fri 8AM – 8PM EST)"],"set_id":"50230cad-3d04-8882-e063-6294a90acf3c","spl_product_data_elements":["ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve Orange aspirin, chlorpheniramine maleate, phenylephrine bitartrate PHENYLEPHRINE BITARTRATE PHENYLEPHRINE FD&C YELLOW NO. 6 SUCRALOSE MANNITOL POTASSIUM BICARBONATE SODIUM BICARBONATE CHLORPHENIRAMINE MALEATE CHLORPHENIRAMINE POVIDONE ANHYDROUS CITRIC ACID ASPIRIN ASPIRIN FD&C RED NO. 40 CALCIUM SILICATE DIMETHICONE SPOTTED ASP;ORANGE Orange Zest"],"spl_unclassified_section":["Drug Facts",""],"stop_use":["Stop use and ask a doctor if ● an allergic reaction occurs. Seek medical help right away. ● you experience any of the following signs of stomach bleeding ● feel faint ● vomit blood ● have bloody or black stools ● have stomach pain that does not get better ● pain or nasal congestion gets worse or lasts more than 7 days ● fever gets worse or lasts more than 3 days ● redness or swelling is present ● new symptoms occur ● ringing in the ears or a loss of hearing occurs ● nervousness, dizziness, or sleeplessness occur"],"version":"2","warnings":["Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include: ● hives ● facial swelling ● asthma (wheezing) ● shock Stomach bleeding warning : This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you ● are age 60 or older ● have had stomach ulcers or bleeding problems ● take a blood thinning (anticoagulant) or steroid drug ● take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ● have 3 or more alcoholic drinks every day while using this product ● take more or for a longer time than directed Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children. Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age Ask a doctor before use if ● stomach bleeding warning applies to you ● you have a history of stomach problems, such as heartburn ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ● you are taking a diuretic ● you have ● asthma ● diabetes ● thyroid disease ● glaucoma ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● a sodium-restricted diet Ask a doctor or pharmacist before use if you are · taking a prescription drug for diabetes, gout or arthritis · taking sedatives or tranquilizers When using this product ● do not exceed recommended dosage ● may cause drowsiness ● alcohol, sedatives, and tranquilizers may increase the drowsiness effect ● avoid alcoholic drinks ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children Stop use and ask a doctor if ● an allergic reaction occurs. Seek medical help right away. ● you experience any of the following signs of stomach bleeding ● feel faint ● vomit blood ● have bloody or black stools ● have stomach pain that does not get better ● pain or nasal congestion gets worse or lasts more than 7 days ● fever gets worse or lasts more than 3 days ● redness or swelling is present ● new symptoms occur ● ringing in the ears or a loss of hearing occurs ● nervousness, dizziness, or sleeplessness occur If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product ● do not exceed recommended dosage ● may cause drowsiness ● alcohol, sedatives, and tranquilizers may increase the drowsiness effect ● avoid alcoholic drinks ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children"]}