{"active_ingredient":["Active ingredient Phenylephrine HCl 0.25%"],"ask_doctor":["Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression"],"dosage_and_administration":["Directions adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before insertion of this product. detach one suppository from the strip; remove the foil wrapper before inserting into the rectum as follows: hold suppository with the rounded end up carefully separate foil tabs by inserting tip of fingernail at end marked “peel down” slowly and evenly peel apart (do not tear) foil by pulling tabs down both sides, to expose the suppository remove exposed suppository from the wrapper insert one suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement children under 12 years of age: consult a doctor"],"effective_time":"20260729","id":"57c2c6b9-a8fa-a1c6-e063-6294a90a97e5","inactive_ingredient":["Inactive ingredients cocoa butter, corn starch, methylparaben, propylparaben"],"indications_and_usage":["Uses helps relieve the local itching and discomfort associated with hemorrhoids temporarily shrinks hemorrhoidal tissue temporarily reduces the swelling associated with irritation in hemorrhoids and other anorectal disorders"],"keep_out_of_reach_of_children":["Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M015"],"brand_name":["up and up"],"generic_name":["PHENYLEPHRINE HYDROCHLORIDE"],"is_original_packager":[true],"manufacturer_name":["Target Corporation"],"package_ndc":["82442-060-12"],"product_ndc":["82442-060"],"product_type":["HUMAN OTC DRUG"],"route":["RECTAL"],"rxcui":["2715398"],"spl_id":["57c2c6b9-a8fa-a1c6-e063-6294a90a97e5"],"spl_set_id":["b42775ae-44fe-487e-b9ca-21d9687020a9"],"substance_name":["PHENYLEPHRINE HYDROCHLORIDE"],"unii":["04JA59TNSJ"]},"other_safety_information":["Other information store at controlled room temperature 20-25°C (68-77°F)"],"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL up&up HEMORRHOIDAL SUPPOSITORIES Phenylephrine HCl 0.25% Helps relieve internal itching,burning and discomfort associated with hemorroids Reduces swolllen hemorrhoidal tissue Also for nighttime relief 12 SUPPOSITORIES Target Hem Supp 12 Count Carton"],"pregnancy_or_breast_feeding":["If pregnant or breast feeding ask a health professional before use."],"purpose":["Purpose Vasoconstrictor"],"questions":["Questions or comments? call 800-910-6874"],"set_id":"b42775ae-44fe-487e-b9ca-21d9687020a9","spl_product_data_elements":["up and up Phenylephrine hydrochloride PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE COCOA BUTTER STARCH, CORN METHYLPARABEN Light yellow Bullet shaped suppository"],"stop_use":["Stop use and ask a doctor if bleeding occurs condition worsens or does not improve within 7 days"],"version":"2","warnings":["Warnings For rectal use only Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression When using this product do not exceed the recommended daily dosage unless directed by a doctor. Stop use and ask a doctor if bleeding occurs condition worsens or does not improve within 7 days If pregnant or breast feeding ask a health professional before use. Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product do not exceed the recommended daily dosage unless directed by a doctor."]}