{"active_ingredient":["Active Ingredients SALICYLIC ACID ...... 0.76% ...... Anti-Acne NIACINAMIDE ...... 2% ...... Fades Acne Scars COPTIS CHINENSIS ROOT EXTRACT ...... 0.24% ......Soothe Acne CENTELLA ASIATICA EXTRACT ...... 0.02% ......Soothe Acne"],"description":["Product Name 456 Acne Relief Cream","Manufacturer Guangzhou Senmai Biotechnology Co.,Ltd.","Address Floor 1-4,Building A,Guanger Smart Industrial Park,No.2 Qianyi East Road, Shiling Town,Huadu District,Guangzhou,Guangdong,CN(China)","Capacity 50ml/1.69fl.oz","Shelf Life Shelf Life ·3 Years","Place of Origin Made in PRC"],"do_not_use":["Do not use on damaged or broken skin."],"dosage_and_administration":["DOSAGE Approximately 0.01-0.02 oz each time."],"effective_time":"20260803","id":"5830fd36-0614-1980-e063-6294a90adfb7","inactive_ingredient":["Inactive Ingredients WATER, BUTYLENE GLYCOL, GLYCERIN, PHELLODENDRON AMURENSE BARK EXTRACT, SALVIA MILTIORRHIZA EXTRACT, LONICERA JAPONICA EXTRACT, ASPALATHUS LINEARIS EXTRACT, SOPHORA FLAVESCENS EXTRACT, SCUTELLARIA BAICALENSIS ROOT EXTRACT, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, ZANTHOXYLUM BUNGEANUM FRUIT EXTRACT, SOPHORA ANGUSTIFOLIA ROOT EXTRACT, CAPSICUM FRUTESCENS FRUIT EXTRACT, PIPER METHYSTICUM ROOT EXTRACT, QUATERNIUM-73, CETEARYL GLUCOSIDE, SORBITAN OLIVATE, CETEARYL ALCOHOL, ACACIA SENEGAL GUM, MALTODEXTRIN, CHITOSAN, CAPRYLIC/CAPRIC TRIGLYCERIDE, DIMETHICONE, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, GLYCERYL STEARATE, PEG-100 STEARATE, INOSITOL, DIMETHYL SULFONE, PHENOXYETHANOL, ETHYLHEXYLGLYCERIN, POLYACRYLAMIDE, C13-14 ISOPARAFFIN, LAURETH-7, CARBOMER, ARGININE, ALLANTOIN, MENTHOL, XANTHAN GUM, HYDROXYETHYLCELLULOSE, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, DISODIUM EDTA, SODIUM HYALURONATE, CERAMIDE NP, TOCOPHEROL"],"indications_and_usage":["Uses STEP 1: Clean the skin and keep it dry. STEP 2: Take an appropriate amount of this product and apply to the skin. STEP 3: Gently massage with your fingertips to promote absorption."],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed,get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M016"],"brand_name":["456 Acne Relief Cream"],"generic_name":["NIACINAMIDE,SALICYLIC ACID,CENTELLA ASIATICA ROOT,COPTIS CHINENSIS ROOT"],"is_original_packager":[true],"manufacturer_name":["Guangzhou Senmai Biotechnology Co.,Ltd."],"package_ndc":["84509-111-01"],"product_ndc":["84509-111"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"spl_id":["5830fd36-0614-1980-e063-6294a90adfb7"],"spl_set_id":["5830fd36-0613-1980-e063-6294a90adfb7"],"substance_name":["SALICYLIC ACID","NIACINAMIDE","COPTIS CHINENSIS ROOT","CENTELLA ASIATICA ROOT"],"unii":["O414PZ4LPZ","25X51I8RD4","CXS4LJR7EL","8MXU1P42J0"]},"package_label_principal_display_panel":["label"],"purpose":["Purpose Acne treatment"],"set_id":"5830fd36-0613-1980-e063-6294a90adfb7","spl_product_data_elements":["456 Acne Relief Cream NIACINAMIDE,SALICYLIC ACID,CENTELLA ASIATICA ROOT,COPTIS CHINENSIS ROOT SALICYLIC ACID SALICYLIC ACID NIACINAMIDE NIACINAMIDE COPTIS CHINENSIS ROOT COPTIS CHINENSIS ROOT CENTELLA ASIATICA ROOT CENTELLA ASIATICA ROOT WATER GLYCERIN BUTYLENE GLYCOL PHELLODENDRON AMURENSE BARK SALVIA MILTIORRHIZA ROOT LONICERA JAPONICA FLOWER ASPALATHUS LINEARIS LEAF SOPHORA FLAVESCENS ROOT SCUTELLARIA BAICALENSIS ROOT HYDROXYACETOPHENONE ZANTHOXYLUM BUNGEANUM FRUIT SOPHORA FLAVESCENS WHOLE CAPSICUM FRUTESCENS FRUIT PIPER METHYSTICUM ROOT QUATERNIUM-73 SORBITAN OLIVATE CETEARYL ALCOHOL MALTODEXTRIN ACACIA SENEGAL GUM CHITOSAN OLIGOSACCHARIDE CAPRYLIC/CAPRIC TRIGLYCERIDE DIMETHICONE SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL GLYCERYL STEARATE PEG-100 STEARATE INOSITOL DIMETHYL SULFONE PHENOXYETHANOL ETHYLHEXYLGLYCERIN POLYACRYLAMIDE (CROSSLINKED; 0.01-0.2 MOLE PERCENT BISACRYLAMIDE) C13-14 ISOPARAFFIN ARGININE ALLANTOIN MENTHOL CARBOMER 1,2-HEXANEDIOL XANTHAN GUM HYDROXYETHYLCELLULOSE MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL SODIUM HYALURONATE CERAMIDE NP TOCOPHEROL EDETATE DISODIUM CETEARYL GLUCOSIDE LAURETH-7"],"version":"1","warnings":["Warnings 1.For external use only.2.Avoid contact with eyes.3.Keep out of reach of children.4.Discontinue use immediately if you experience any allergic reactions and consult a physician."],"when_using":["When using this product 1. It is recommended to test the product behind the ear beforeuse. If discomfort is felt, do not use. 2. If it accidentally enters the eyes, rinse immediately with water. 3. Keep out of reach of children. Do not use for children under 3 years old. 4. Do not expose to direct sunlight and high temperatures. 5. This product contains salicylic acid."]}