{"dosage_and_administration":["Use once daily in the morning. Apply 5 - 7 drops to the entire face, or as directed by your skin care physician. Massage in gently. If no improvement is seen after three ( 3 ) months of treatrment, use of this product should be discontinued. Sun exposure should be limited by using a sunscreen agent, a sun blocking agent, or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening from reoccurring.","Use daily in the evening. Dispense a small amount ( approximately 1 - 2 pea - sized drops) and apply to the entire face. Massage in gently. If no improvement is seen after three ( 3 ) months, use of this product should be discontinued. Sun exposure should be limited by using a sunscreen agent, a sun blocking agent, or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening from reoccurring."],"dosage_forms_and_strengths":["Active Ingredient Hydroquinonone USP, 4 % (40 mg /g ) Inactive ingredients propylene glycol, water, ascorbic acid, propylene carbonate, sodium lauryl sulfate","Each gram of Obagi - C Rx Therapy Night Cream contains: Active Ingredient: Hydroquinone USP, 4 % (40 Mg / g)"],"effective_time":"20170613","id":"58a5cbb0-bf9b-4fde-a3cf-80d8e8a69b26","indications_and_usage":["The gradual bleach hyperpigmented skin conditions such as chloasma, melasma, freckles, lengitines, and other unwanted areas of melanin hyperpigmentation.","The gradual bleaching of hyperpigmented skin conditions such a chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation."],"openfda":{},"package_label_principal_display_panel":["copy of label"],"set_id":"f9cb3088-02fe-4dee-8e12-b9deb60d6460","spl_product_data_elements":["Obagi HYDROQUINONE Obagi - C HYDROQUINONE HYDROQUINONE HYDROQUINONE WATER GLYCERIN CETYL ALCOHOL PPG-2 MYRISTYL ETHER PROPIONATE SODIUM LAURYL SULFATE TROLAMINE SALICYLATE LACTIC ACID, UNSPECIFIED FORM PHENYL TRIMETHICONE .ALPHA.-TOCOPHEROL ACETATE SODIUM DITHIONATE ASCORBIC ACID METHYLPARABEN EDETATE DISODIUM PROPYLPARABEN BUTYLATED HYDROXYTOLUENE Obagi - C HYDROQUINONE HYDROQUINONE HYDROQUINONE PROPYLENE GLYCOL WATER ASCORBIC ACID PROPYLENE CARBONATE SODIUM LAURYL SULFATE Obagi OCTINOXATE, ZINC OXIDE OCTINOXATE OCTINOXATE ZINC OXIDE ZINC OXIDE CYCLOMETHICONE 5 WATER PEG-10 DIMETHICONE (600 CST) PENTYLENE GLYCOL STEARYL ALCOHOL POLYOXYL 20 CETOSTEARYL ETHER PHENYL TRIMETHICONE PEG-40 STEARATE SODIUM DIHYDROXYCETYL PHOSPHATE HYDROGENATED PALM GLYCERIDES CITRIC ACID MONOHYDRATE CETOSTEARYL ALCOHOL .ALPHA.-TOCOPHEROL ACETATE 1,2-HEXANEDIOL CAPRYLYL GLYCOL TROPOLONE CHLORPHENESIN XANTHAN GUM POTASSIUM SORBATE SODIUM BENZOATE TETRAHEXYLDECYL ASCORBATE UBIDECARENONE EDETATE DISODIUM METHYLISOTHIAZOLINONE HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (100000 MPA.S AT 1.5%) SQUALANE POLYSORBATE 60"],"spl_unclassified_section":["WELCOME TO THE OBAGI - C RX SYSTEM OF SKIN CARE PRODUCTS See enclosed packet for full prescribing information For external use only Rx only C-Clarifying Serum Normal to Dry (Skin Lightening Serum) 1 fl. oz. (30 mL.) Hydroquinone USP, 4% Rx Only AM Antioxidant serum containing Vitamin C and prescription-strength hydroquinone. This patented formulation for normal to dry skin reduces the appearance of dark spots for a lighter, brighter complexion.","C - Therapy Night Cream (Skin Lightener) Net wt 2 oz. (57 g) Hydroquinone USP, 4 % Rx only PM A rich moisturizer that works while you sleep to renew and rejuvenate your skin. The C - Therapy Night Cream us uniquely formulated with prescription - strength hydroquinone to gradually diminish the appearance of dark spots and delivers Vitamins C and E during the skin's nightly renewal process.","Contains sodium metabisulfate, a sulfate that may cause allergic - type reactions including anaphylactic symptoms and life - threatening or less severe asthmatic episodes in certain susceptible people. The overall presence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.","Inactive Ingredients water, glycerin, cetyl alcohol, PPG - 2 myristyl ether propionate, sodium lauryl sulfate, TEA - salicylate, lactic acid, phenyl trimethicone, tocopheryl acetate, sodium metabisulfite, ascorbic acid, methylparaben, disodium EDTA, propylparaben, saponins, BHT","See enclosed Package Insert for full prescribing information Rx ONLY. FOR EXTERNAL USE ONLY","Travel Bag and Patient Instruction Guide","Sun Shield Broad Spectrum SPF 50 Matte Net wt. 3 oz. ( 85 g ) This sunscreen contains UVB absorption and UVA protection in an elegant matte finish that is non - comedogenic, hypoallergenic, non - acnegenic, and dermatologist tested. Sheer, PABA free, and fragrance free for all skin types.","Active Ingredients Octinoxate 7.5 % Zinc Oxide 10.5 %","Purpose Sunscreen","Inactive Ingredients 1,2 - hexanediol, caprylyl glycol, ceteareth - 20, cetearyl alcohol, chlorphenesin, citric acid, cyclopentasilozane, dimethicone, dimethicone crosspolymer - 3, disodium EDTA, glycerin, hydrogenated palm glycerides, hydroxyethyl arylate / sodium acryloyldimethyl taurate copolymer, methylisothiazolinone, PEG - 40 stearate, pentylene glycol, phenoxyehtanol, phenyl trimethicone, polysilicone - 11, polysorbate 60, potassium sorbate, sodium benzoate, sodium dihydroxycetyl phosphate, sodium polyacrylate, squalane, stearyl alcohol, tetrahexyldecyl ascorbate, tropolone, water, xanthan gum","Questions or comments? 1.800.636.7546 Monday - Friday 9 am - 4 pm Pacific Time"],"storage_and_handling":["Store at controlled room temperature: 15 C - 25 C (59 F - 77 F) protect t product from excessive heat and direct sun"],"version":"3","warnings":["Warnings Avoid contact with eyes, nose, mouth or lips. In case of accidental contact, patient should rinse eyes thoroughly with water and contact physician. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure maintains melanocytic activity.","Warnings Avoid contact with eyes, nose, mouth or lips. In case of accidental contact, patient should rinse eyes thoroughly with water and contact physician.Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity."]}