{"active_ingredient":["Active ingredient Menthol 8.0%"],"dosage_and_administration":["Directions Adults and children 2 years of age and older: apply directly onto affected area without the need to rub, massage or bandage repeat if necessary, but do not apply more than 3 to 4 times daily wash hands after use Children under 2 years of age: do not use, consult a doctor."],"effective_time":"20260901","id":"5a6e9886-23df-e0ee-e063-6294a90a5e48","inactive_ingredient":["Inactive ingredients acrylic acid/vinyl ester copolymer, dimethylsulfone (MSM), eucalyptus oil, glucosamine sulfate, hydroxypropylcellulose, PEG-8 dimethicone, pentylene glycol, peppermint oil, SD alcohol 39C, triethanolamine, water (USP)"],"indications_and_usage":["Uses For the temporary relief of minor aches and pains of muscles and joints associated with: simple backache arthritis strains bruises sprains"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M017"],"brand_name":["ActivICE"],"generic_name":["MENTHOL"],"is_original_packager":[true],"manufacturer_name":["Medline Industries, LP"],"package_ndc":["53329-984-04","53329-984-23","53329-984-25","53329-984-30","53329-984-06","53329-984-16"],"product_ndc":["53329-984"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["283257","2119857"],"spl_id":["5a6e9886-23df-e0ee-e063-6294a90a5e48"],"spl_set_id":["834adeb9-38ad-0cfe-e053-2991aa0af82f"],"substance_name":["MENTHOL"],"unii":["L7T10EIP3A"]},"other_safety_information":["Other information store at room temperature"],"package_label_principal_display_panel":["Package Label Curad Label V3 RF23MFO MDSAICE16"],"pregnancy_or_breast_feeding":["If pregnant or breastfeeding, ask a health professional before use."],"purpose":["Purpose Topical Analgesic"],"questions":["Questions or comments? 1-800-MEDLINE (633-5463) Monday-Friday 9AM-5PM CST"],"recent_major_changes":["Updated directions [dosage and administration section]"],"set_id":"834adeb9-38ad-0cfe-e053-2991aa0af82f","spl_product_data_elements":["ActivICE menthol MENTHOL MENTHOL PENTYLENE GLYCOL WATER PEG-8 DIMETHICONE TROLAMINE PEPPERMINT OIL PEPPERMINT ALCOHOL HYDROXYPROPYL CELLULOSE (1600000 WAMW) EUCALYPTUS OIL GLUCOSAMINE SULFATE DIMETHYL SULFONE"],"spl_unclassified_section":["Manufacturing Information www.medline.com Manufactured in USA for: Medline Industries, LP, Three Lakes Drive, Northfield, IL 60093 USA 1-800-MEDLINE REF: MDSAICEGELR, MDSAICEGEL, MDSAICE16"],"stop_use":["Stop use and ask doctor if condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days redness is present excessive irritation of the skin develops"],"version":"12","warnings":["Warnings For external use only. Avoid contact with eyes. Flammable: keep away from fire or flame. When using this product use only as directed do not bandage tightly or use with heating pad do not apply to wounds or damaged skin Stop use and ask doctor if condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days redness is present excessive irritation of the skin develops If pregnant or breastfeeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product use only as directed do not bandage tightly or use with heating pad do not apply to wounds or damaged skin"]}