{"active_ingredient":["Active ingredient Povidone-iodine 10% (equivalent to 1% available iodine)"],"ask_doctor":["Ask a doctor before use if injuries are deep or puncture wounds serious burns"],"do_not_use":["Do not use in the eyes on individuals allergic or sensitive to iodine"],"dosage_and_administration":["Directions apply topically as needed"],"effective_time":"20260902","id":"5a86eb3c-9bed-842f-e063-6294a90adff3","inactive_ingredient":["Inactive ingredients citric acid, disodium phosphate, nonoxynol-9, sodium hydroxide, water"],"indications_and_usage":["Uses antiseptic skin preparation single use when used for patient preoperative skin preparation"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of accidental ingestion, seek professional assistance or consult a poison control center immediately."],"openfda":{"application_number":["505G(a)(3)"],"brand_name":["Aplicare Povidone-Iodine"],"generic_name":["POVIDONE-IODINE"],"is_original_packager":[true],"manufacturer_name":["Aplicare Products, LLC"],"nui":["N0000175486","M0011640"],"package_ndc":["52380-1905-2","52380-1905-4","52380-1905-8","52380-1905-6","52380-1905-7","52380-1905-9","52380-1905-3","52380-1905-0"],"pharm_class_cs":["Iodine [CS]"],"pharm_class_epc":["Antiseptic [EPC]"],"product_ndc":["52380-1905"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["312564","617973"],"spl_id":["5a86eb3c-9bed-842f-e063-6294a90adff3"],"spl_set_id":["7302a2f8-a600-4200-bc4e-309e4c190fe5"],"substance_name":["POVIDONE-IODINE"],"unii":["85H0HZU99M"]},"other_safety_information":["Other information not made with natural rubber latex for hospital or professional use only"],"package_label_principal_display_panel":["Package Label Each"],"purpose":["Purpose Antiseptic"],"questions":["Questions or comments? www.medline.com 1-800-Medline"],"recent_major_changes":["Recent Major Changes Update to indications and usage section July 2026 Update to indications and usage section September 2, 2026"],"set_id":"7302a2f8-a600-4200-bc4e-309e4c190fe5","spl_product_data_elements":["Aplicare Povidone-Iodine Povidone-Iodine POVIDONE-IODINE IODINE SODIUM PHOSPHATE, DIBASIC SODIUM HYDROXIDE NONOXYNOL-9 WATER CITRIC ACID MONOHYDRATE"],"spl_unclassified_section":["Manufacturing Information Manufactured in USA by Medline Industries, LP, Three Lakes Drive, Northfield, IL 60093 USA. www.medline.com 1-800-Medline REF: APL82332"],"stop_use":["Stop use and ask a doctor if infection occurs redness, irritation, swelling or pain persists or increases"],"version":"20","warnings":["Warnings For external use only Avoid \"pooling\" beneath patient. Prolonged exposure to wet solution may cause skin irritation. Do not use in the eyes on individuals allergic or sensitive to iodine Ask a doctor before use if injuries are deep or puncture wounds serious burns Stop use and ask a doctor if infection occurs redness, irritation, swelling or pain persists or increases Keep out of reach of children. In case of accidental ingestion, seek professional assistance or consult a poison control center immediately."]}