{"active_ingredient":["Active Ingredient Povidone-iodine 7.5% (equivalent to 0.75% available iodine)"],"ask_doctor":["Ask a doctor before use if injuries are deep or puncture wounds serious burns"],"do_not_use":["Do not use in the eyes on individuals allergic or sensitive to iodine"],"dosage_and_administration":["Directions apply topically as needed"],"effective_time":"20260902","id":"5a8748b6-17b0-cdca-e063-6394a90ad140","inactive_ingredient":["Inactive ingredients ammonium nonoxynol-4 sulfate, citric acid, disodium phosphate, nonoxynol-9, sodium hydroxide, water"],"indications_and_usage":["Use • antiseptic skin preparation • single use when used for patient preoperative skin preparation"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of accidental ingestion, seek professional assistance or consult a poison control center immediately."],"openfda":{"application_number":["505G(a)(3)"],"brand_name":["Aplicare Povidone-iodine Scrub"],"generic_name":["POVIDONE-IODINE"],"is_original_packager":[true],"manufacturer_name":["Aplicare Products, LLC"],"nui":["N0000175486","M0011640"],"package_ndc":["52380-4802-8"],"pharm_class_cs":["Iodine [CS]"],"pharm_class_epc":["Antiseptic [EPC]"],"product_ndc":["52380-4802"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["314188"],"spl_id":["5a8748b6-17b0-cdca-e063-6394a90ad140"],"spl_set_id":["b8a23a29-2541-4987-a534-17a6369a6c8d"],"substance_name":["POVIDONE-IODINE"],"unii":["85H0HZU99M"]},"other_safety_information":["Other information Not made with natural rubber latex for hospital or professional use only"],"package_label_principal_display_panel":["Package Label Each"],"purpose":["Purpose Antiseptic"],"questions":["Questions or comments? www. medline.com 1-800-Medline"],"recent_major_changes":["Updated dosage and administration section on September 2, 2026"],"set_id":"b8a23a29-2541-4987-a534-17a6369a6c8d","spl_product_data_elements":["Aplicare Povidone-iodine Scrub Povidone-iodine POVIDONE-IODINE IODINE SODIUM PHOSPHATE, DIBASIC ANHYDROUS CITRIC ACID SODIUM HYDROXIDE NONOXYNOL-9 AMMONIUM NONOXYNOL-4 SULFATE WATER"],"spl_unclassified_section":["Manufacturing Information Manufactured in USA by Medline Inustries, LP, Three Lakes Drive, Northfield, IL 60093 USA www.medline.com 1-800-Medline REF: APL82364K"],"stop_use":["Stop use and ask a doctor if infection occurs redness, irritation, swelling or pain persists or increases"],"version":"15","warnings":["Warnings For external use only Avoid \"pooling\" beneath patient. Prolonged exposure to wet solution may cause skin irritation. Do not use in the eyes on individuals allergic or sensitive to iodine Ask a doctor before use if injuries are deep or puncture wounds serious burns Stop use and ask a doctor if infection occurs redness, irritation, swelling or pain persists or increases Keep out of reach of children. In case of accidental ingestion, seek professional assistance or consult a poison control center immediately."]}