{"active_ingredient":["Active Ingredient Active Ingredient Bismuth Subsalicylate 525 mg"],"ask_doctor":["Ask a doctor before use if you have Ask a doctor before use if you have fever mucus in the stool"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist Ask a doctor or pharmacist if you are taking any drug for anticoagulation (thinning of the blood) diabetes gout arthritis"],"do_not_use":["Do not use if you have Do not use if you have an ulcer a bleeding problem bloody or black stool"],"dosage_and_administration":["Directions Directions shake well before use, only with dosing cup provided drink plenty of clear fluids to help prevent dehydration Adults and children: (12 years and over) 30 mL (1 dose) every 1/2 hour or 60 mL (2 doses) every hour as needed for diarrhea / travelers' diarrhea 30 mL (1 dose) every 1/2 hour as needed for over indulgence (upset stomach, heartburn, indigestion, nausea) do not exceed 8 doses (240 mL) in 24 hours use until diarrhea stops, but not more than 2 days Children under 12 years: Ask a doctor"],"effective_time":"20260910","id":"5b231ff5-2255-6463-e063-6294a90ab02b","inactive_ingredient":["Inactive ingredients Inactive ingredients anhydrous citric acid, benzoic acid, D&C red # 22, D&C Red # 28, flavor, purified water, salicylic acid, sodium citrate, sodium salicylate, sorbic acid, sucralose, xanthan gum"],"indications_and_usage":["Uses Uses releives travelers' diarrhea diarrhea upset stomach due to overindulgence in food and drin, including: heartburn indigestion nausea gas belching fullness"],"keep_out_of_reach_of_children":["Keep out of reach of children Keep out of reach of children. In case of accidental overdose, contact a physician or poison control center right away (1-800-222-1222)."],"openfda":{"application_number":["M008"],"brand_name":["Medique Diotame Instydose"],"generic_name":["BISMUTH SUBSALICYLATE"],"is_original_packager":[true],"manufacturer_name":["Unifirst First Aid Corporation"],"nui":["M0002611","N0000180183"],"package_ndc":["47682-670-69"],"pharm_class_cs":["Bismuth [CS]"],"pharm_class_epc":["Bismuth [EPC]"],"product_ndc":["47682-670"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["308762"],"spl_id":["5b231ff5-2255-6463-e063-6294a90ab02b"],"spl_set_id":["5b214128-6980-0f84-e063-6294a90ad8ca"],"substance_name":["BISMUTH SUBSALICYLATE"],"unii":["62TEY51RR1"],"upc":["0347682230692"]},"other_safety_information":["Other information Other information each 30 mL dose contains: sodium 22 mg, salicylate 249 mg protect from freezing avoid excessive heat (over 104°F or 40°C) TAMPER -EVIDENT FEATURE: Do not use if printed safety seal is torn, broken, or missing."],"package_label_principal_display_panel":["Medique Diotame Instydose 5-19-26 Medique Diotame InstyDose® Upset Stomach / Diarrhea Relief Pull to Open Bismuth Subsalicylate 525 mg Tamper Evident Unit Dose 6-30 mL Liquid Cups 23069 Diotame InstyDose 5-19-26"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purpose Purpose Upset stomach reliever / antidiarrheal"],"questions":["Qustions or comments Questions or comments? 1-800-634-7680"],"set_id":"5b214128-6980-0f84-e063-6294a90ad8ca","spl_product_data_elements":["Medique Diotame Instydose Bismuth Subsalicylate BISMUTH SUBSALICYLATE SALICYLIC ACID SODIUM SALICYLATE SODIUM CITRATE WATER ANHYDROUS CITRIC ACID SALICYLIC ACID BENZOIC ACID XANTHAN GUM D&C RED NO. 22 D&C RED NO. 28 SORBIC ACID SUCRALOSE"],"spl_unclassified_section":["Drug Facts Drug Facts"],"stop_use":["Stop use and ask a doctor if Stop use and ask a doctor if symptoms get worse or last for more than 2 days ringing in the ears or loss of hearing occurs diarrhea lasts more than 2 days"],"version":"2","warnings":["Warnings Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's Syndrom, a rare but serious illness. Allergy alert: Contains salicylate. Do not take if you are: allergic to salicylates (including aspirin) taking other salicylate products","When using this product When using this product, a temporary but harmless darkening of the stool and/or tongue may occur"]}