{"active_ingredient":["Active ingredient Hydroquinone USP, 4% (40 mg/g)","Active ingredient Hydroquinone USP, 4% (40 mg/g)","Active ingredients Purpose Octinoxate 7.5% Sunscreen Zinc Oxide 10.5% Sunscreen"],"active_ingredient_table":["<table width=\"50%\"> <col width=\"50%\" align=\"left\" valign=\"top\"/> <col width=\"50%\" align=\"right\" valign=\"top\"/> <thead> <tr> <th> <content styleCode=\"italics\">Active ingredients</content> </th> <th> <content styleCode=\"italics\">Purpose</content> </th> </tr> </thead> <tbody> <tr> <td>Octinoxate 7.5%</td> <td>Sunscreen</td> </tr> <tr> <td>Zinc Oxide 10.5%</td> <td>Sunscreen</td> </tr> </tbody> </table>"],"do_not_use":["Avoid getting into eyes. For external use only.","Avoid getting into eyes. For external use only.","Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes thoroughly with water and contact physician. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.","Avoid getting into eyes. For external use only.","Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes thoroughly with water and contact physician. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.","For external use only Do not use on damaged or broken skin"],"dosage_and_administration":["Directions Use twice daily, morning and evening. Massage a small amount of cleanser and water onto skin. Rinse with lukewarm water and gently pat dry.","Directions Use daily, in the morning and evening after cleansing. Saturate a cotton pad and gently wipe over entire face. Do not rinse.","Dosage and administration Use daily, in the morning and evening. Squeeze a small amount (approximately 1-2 pea-sized amounts) onto your hand. Apply evenly to the entire face, extending to the hairline, over the ears, and ending with a feathering motion, or as directed by your physician. If no improvement is seen after three (3) months of treatment, use of this product should be discontinued. Sun exposure should be limited by using a sunscreen agent, a sun blocking agent, or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening from reoccurring.","Directions Use daily, in the morning. Squeeze a small amount (approximately 1-2 pea-sized drops) onto your hands. Using your fingertips, apply evenly to the entire face. Massage until completely absorbed.","Dosage and administration Use daily, in the evening. Squeeze a small amount (approximately 1-2 pea-sized drops) onto your hand. Apply evenly to the entire face, or as directed by your skin care physician. If no improvement is seen after three (3) months of treatment, use of this product should be discontinued. Sun exposure should be limited by using a sunscreen agent, a sun blocking agent, or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening from reoccurring.","Directions apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every 2 hours children under 6 months: Ask a doctor Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum value of SPF 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m.-2 p.m. wear long-sleeved shirts, pants, hats, and sunglasses"],"effective_time":"20191204","id":"610ddcff-3c89-42c0-97cb-0d71f2f70449","inactive_ingredient":["Ingredients water (aqua), cocamidopropyl betaine, glycerin, sodium lauroyl oat amino acids, aloe barbadensis leaf juice (aloe barbadensis), sodium laureth sulfate, glycereth-7, prunus armeniaca (apricot) kernel oil, panthenol, acrylates/C10-30 alkyl acrylate crosspolymer, oleyl lactate, ethoxydiglycol, triethanolamine, salvia officinalis (sage) leaf extract (salvia officinalis), borago officinalis extract, saponins, phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben, fragrance (parfum), yellow 5 (CI 19140)","Ingredients water (aqua), hamamelis virginiana (witch hazel) water, aloe barbadensis leaf juice (aloe barbadensis), potassium alum, sodium PCA, panthenol, DMDM hydantoin, polysorbate 80, allantoin, glycerin, salvia officinalis (sage) leaf extract (salvia officinalis), borago officinalis extract, calendula officinalis flower extract (calendula officinalis), saponins, iodopropynyl butylcarbamate, fragrance (parfum), blue 1 (CI 42090)","Inactive ingredients water, cetyl alcohol, glycerin, sodium lauryl sulfate, stearyl alcohol, lactic acid, tocopheryl acetate, ascorbic acid, sodium metabisulfite, disodium EDTA, methylparaben, BHT, propylparaben, saponins, butylparaben","Ingredients water (aqua), ethoxydiglycol, glycerin, phytic acid, cetearyl alcohol, glyceryl stearate, PEG-100 stearate, canola oil, isohexadecane, magnesium aluminum silicate, potassium cetyl phosphate, cetyl alcohol, bis-diglyceryl polyacyladipate-2, dimethicone, polysorbate 60, PEG-150 stearate, steareth-20, xanthan gum, glycereth-7, tocopheryl acetate, saponins, phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben","Inactive ingredients water, glycerin, cetyl alcohol, PPG-2 myristyl ether propionate, sodium lauryl sulfate, TEA-salicylate, lactic acid, phenyl trimethicone, tocopheryl acetate, sodium metabisulfite, ascorbic acid, methylparaben, disodium EDTA, propylparaben, saponins, BHT","Inactive ingredients 1,2-hexanediol, caprylyl glycol, ceteareth-20, cetearyl alcohol, chlorphenesin, citric acid, cyclopentasiloxane, dimethicone crosspolymer-3, disodium EDTA, hydrogenated palm glycerides, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, methylisothiazolinone, PEG-10 dimethicone, PEG-40 stearate, pentylene glycol, phenyl trimethicone, polysilicone-11, polysorbate 60, potassium sorbate, sodium benzoate, sodium dihydroxycetyl phosphate, squalane, stearyl alcohol, tetrahexyldecyl ascorbate, tocopheryl acetate, tropolone, ubiquinone, water, xanthan gum"],"indications_and_usage":["Indications and usage The gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation.","Indications and usage The gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation. Specially formulated for blending purposes as part of the Obagi Nu-Derm System.","Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun"],"keep_out_of_reach_of_children":["Keep out of reach of children.","Keep out of reach of children.","Keep out of reach of children.","Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - Kit Carton NDC# 62032-516-60 OBAGI ® MEDICAL NU-DERM ® SYSTEM NORMAL DRY Skin Transformation Trial Kit PRINCIPAL DISPLAY PANEL - Kit Carton"],"purpose":["Active ingredients Purpose Octinoxate 7.5% Sunscreen Zinc Oxide 10.5% Sunscreen"],"purpose_table":["<table width=\"50%\"> <col width=\"50%\" align=\"left\" valign=\"top\"/> <col width=\"50%\" align=\"right\" valign=\"top\"/> <thead> <tr> <th> <content styleCode=\"italics\">Active ingredients</content> </th> <th> <content styleCode=\"italics\">Purpose</content> </th> </tr> </thead> <tbody> <tr> <td>Octinoxate 7.5%</td> <td>Sunscreen</td> </tr> <tr> <td>Zinc Oxide 10.5%</td> <td>Sunscreen</td> </tr> </tbody> </table>"],"questions":["Questions or comments? 1.800.636.7546 Monday–Friday 9 a.m.-4 p.m. Pacific Time"],"set_id":"376dd650-fa5f-42a7-b974-6f538a28f7f2","spl_product_data_elements":["nu-derm system normal-dry skin transformation trial Hydroquinone, Octinoxate, and Zinc Oxide NU-DERM BLENDER Skin Lightener and Blending HYDROQUINONE HYDROQUINONE HYDROQUINONE EDETATE DISODIUM PPG-2 MYRISTYL ETHER PROPIONATE TROLAMINE SALICYLATE SODIUM LAURYL SULFATE CETYL ALCOHOL GLYCERIN LACTIC ACID, UNSPECIFIED FORM .ALPHA.-TOCOPHEROL ACETATE ASCORBIC ACID SODIUM METABISULFITE WATER METHYLPARABEN PROPYLPARABEN BUTYLATED HYDROXYTOLUENE PHENYL TRIMETHICONE NU-DERM CLEAR Skin Bleaching and Corrector HYDROQUINONE HYDROQUINONE HYDROQUINONE EDETATE DISODIUM BUTYLPARABEN STEARYL ALCOHOL SODIUM LAURYL SULFATE CETYL ALCOHOL GLYCERIN LACTIC ACID, UNSPECIFIED FORM .ALPHA.-TOCOPHEROL ACETATE ASCORBIC ACID SODIUM METABISULFITE WATER METHYLPARABEN PROPYLPARABEN BUTYLATED HYDROXYTOLUENE NU-DERM SUN SHIELD BROAD SPECTRUM SPF 50 MATTE SUNSCREEN OCTINOXATE AND ZINC OXIDE OCTINOXATE OCTINOXATE ZINC OXIDE ZINC OXIDE CYCLOMETHICONE 5 WATER PEG-10 DIMETHICONE (600 CST) PENTYLENE GLYCOL STEARYL ALCOHOL POLYOXYL 20 CETOSTEARYL ETHER PHENYL TRIMETHICONE PEG-40 STEARATE SODIUM DIHYDROXYCETYL PHOSPHATE HYDROGENATED PALM GLYCERIDES CITRIC ACID MONOHYDRATE CETOSTEARYL ALCOHOL .ALPHA.-TOCOPHEROL ACETATE 1,2-HEXANEDIOL CAPRYLYL GLYCOL TROPOLONE CHLORPHENESIN XANTHAN GUM POTASSIUM SORBATE SODIUM BENZOATE TETRAHEXYLDECYL ASCORBATE UBIDECARENONE EDETATE DISODIUM METHYLISOTHIAZOLINONE HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (100000 MPA.S AT 1.5%) SQUALANE POLYSORBATE 60 NU-DERM GENTLE CLEANSER inert WATER GLYCERIN PHENOXYETHANOL METHYLPARABEN PROPYLPARABEN BUTYLPARABEN ETHYLPARABEN ISOBUTYLPARABEN SODIUM LAUROYL OAT AMINO ACIDS COCAMIDOPROPYL BETAINE SODIUM LAURETH-3 SULFATE ALOE VERA LEAF GLYCERETH-7 PANTHENOL DIETHYLENE GLYCOL MONOETHYL ETHER TROLAMINE SAGE FD&C YELLOW NO. 5 APRICOT KERNEL OIL OLEYL LACTATE CARBOMER COPOLYMER TYPE B (ALLYL PENTAERYTHRITOL CROSSLINKED) NU-DERM TONER inert WATER GLYCERIN SODIUM PYRROLIDONE CARBOXYLATE DMDM HYDANTOIN IODOPROPYNYL BUTYLCARBAMATE POTASSIUM ALUM PANTHENOL SAGE CALENDULA OFFICINALIS FLOWER POLYSORBATE 80 ALLANTOIN ALOE VERA LEAF FD&C BLUE NO. 1 HAMAMELIS VIRGINIANA TOP WATER NU-DERM EXFODERM inert WATER GLYCERIN METHYLPARABEN PROPYLPARABEN POLYSORBATE 60 CETOSTEARYL ALCOHOL STEARETH-20 CANOLA OIL ISOHEXADECANE MAGNESIUM ALUMINUM SILICATE CETYL ALCOHOL FYTIC ACID GLYCERYL MONOSTEARATE PEG-100 STEARATE DIMETHICONE PEG-150 STEARATE PHENOXYETHANOL BUTYLPARABEN ETHYLPARABEN ISOBUTYLPARABEN POTASSIUM CETYL PHOSPHATE XANTHAN GUM .ALPHA.-TOCOPHEROL ACETATE GLYCERETH-7 DIETHYLENE GLYCOL MONOETHYL ETHER"],"spl_unclassified_section":["Gentle Cleanser 2 fl. oz. (59 mL.) AM+PM A mild facial cleanser that provides gentle yet effective cleansing for normal to dry skin. For skin that's beautifully clean and fresh, the Nu-Derm Gentle Cleanser instantly dissolves excess oil, makeup, and other everyday impurities, without stripping your skin of its natural protective oils, and prepares your skin for the next step in your skin care regimen.","Toner 2 fl. oz. (59 mL.) AM+PM An essential step in your daily skin care routine, this alcohol-free, non-drying toner helps adjust your skin's pH for increased penetration of product ingredients. Use after cleansing to remove impurities and dead skin cells and to prepare the skin for hydration or appropriate products.","Clear (Skin Bleaching and Corrector Cream) NDC 62032-101-36 Net wt. 2 oz. (57 g.) Hydroquinone USP, 4% Rx Only AM+PM Dark spots may appear on the surface of your skin, but they actually start deep within the skin's layers. This gentle yet effective formula absorbs into the layers of your skin to deliver prescription-strength hydroquinone, helping to correct the appearance of age and sun spots for a healthier, more even complexion.","Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people. Each gram of Obagi Nu-Derm Clear contains:","See enclosed Package Insert for full prescribing information. Rx ONLY. FOR EXTERNAL USE ONLY.","Exfoderm ® (Skin Smoothing Lotion) Net wt. 1 oz. (28 g.) AM A lightweight lotion that exfoliates the top layer of skin, removing dull, old skin cells while promoting new skin cells for a brighter complexion. Specifically developed for normal to dry skin, this gentle, skin-enhancing formula contains a plant acid (phytic acid) to help transform the appearance of damaged skin and reveal your skin's radiance.","Blender ® (Skin Lightener and Blending Cream) NDC 62032-100-36 Net wt. 1 oz. (28 g.) Hydroquinone USP, 4% Rx Only PM A unique formula containing prescription-strength hydroquinone for the gradual lightening of sun spots, age spots, and other types of hyperpigmentation (discoloration). Specially formulated to optimize the delivery of product ingredients in the Nu-Derm System, this skin lightener helps reduce the signs of aging and correct uneven skin tone. May be used with Tretinoin Cream Tretinoin cream is indicated for topical application in the treatment of acne vulgaris. or Refissa Refissa [Tretinoin Cream, USP (Emollient) 0.05%] is indicated as an adjunctive agent for use in the mitigation (palliation) of fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin in patients who do not achieve such palliation using comprehensive skin care and sun avoidance programs. REFISSA DOES NOT ELIMINATE WRINKLES, REPAIR SUN-DAMAGED SKIN, REVERSE PHOTOAGING, or RESTORE A MORE YOUTHFUL or YOUNGER DERMAL HISTOLOGIC PATTERN. as prescribed by a physician.","See enclosed Package Insert for full prescribing information. Rx ONLY. FOR EXTERNAL USE ONLY.","Travel Bag and Patient Instruction Guide Store at controlled room temperature 15°C–25°C (59°F–77°F). Blender, Exfoderm, Nu-Derm, Obagi and the Obagi logo are registered trademarks of OMP, Inc. Refissa is a registered trademark or Spear Pharmaceuticals, Inc. Distributed by OMP, Inc., Long Beach, CA 90806 ©2012 Obagi Medical Products, Inc. All Rights Reserved. OBAGI.COM Made in USA 40706310Z 7063","Sun Shield Matte Broad Spectrum SPF 50 Net wt. 1 oz. (28 g.) This sunscreen combines UVB absorption and UVA protection in an elegant, matte finish that is non-comedogenic, allergy tested, and dermatologist tested. Sheer, PABA free, and fragrance free for all skin types.","Drug Facts"],"stop_use":["Stop use and ask a doctor if rash occurs"],"storage_and_handling":["Other information Store at controlled room temperature: 15°C–25°C (59°F–77°F) protect this product from excessive heat and direct sun"],"version":"3","warnings":["Warnings Avoid getting into eyes. For external use only. Keep out of reach of children.","Warnings Avoid getting into eyes. For external use only. Keep out of reach of children.","Warnings Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes thoroughly with water and contact physician. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.","Warnings Avoid getting into eyes. For external use only. Keep out of reach of children.","Warnings Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes thoroughly with water and contact physician. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity. Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people. Each gram of Obagi Nu-Derm Blender contains:","Warnings For external use only Do not use on damaged or broken skin Stop use and ask a doctor if rash occurs When using this product keep out of eyes. Rinse with water to remove. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product keep out of eyes. Rinse with water to remove."]}