{"active_ingredient":["ACTIVE INGREDIENTS: (in each spray) Benzoicum Acidum 15X, Berberis Vulgaris 15X, Bryonia 15X, Cantharis 15X, Carduus Benedictus 15X, Carduus Marianus 3X, Ceanothus Americanus 15X, Chelidonium Majus 15X, Chionanthus Virginica 15X, Cinchona Officinalis 15X, Cynara Scolymus 3X, Dioscorea Villosa 15X, Dolichos Pruriens 15X, Iris Versicolor 15X, Juniperus Communis 15X, Nux Vomica 15X, Ptelea Trifoliata 15X, Solidago Virgaurea 3X, Taraxacum Officinale 3X, 15X, Uricum Acidum 15X."],"dosage_and_administration":["DIRECTIONS: Adults and children 12 years and older, hold nozzle 1\" from mouth, spray twice and swallow at bedtime, or use as directed by your healthcare practitioner. Consult a physician for use in children under 12 years of age."],"effective_time":"20260306","id":"71920d36-a413-44e1-9e44-0342d3aea96f","inactive_ingredient":["INACTIVE INGREDIENTS: Cane alcohol USP, purified water USP."],"indications_and_usage":["USES: ■ Improves liver, kidney and colon functions. ■ Reduces symptoms associated with toxic conditions."],"keep_out_of_reach_of_children":["KEEP OUT OF REACH OF CHILDREN: In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"brand_name":["Advance Plus"],"generic_name":["CARDUUS MARIANUS, CYNARA SCOLYMUS, SOLIDAGO VIRGAUREA, TARAXACUM OFFICINALE, BENZOICUM ACIDUM, BERBERIS VULGARIS, BRYONIA (ALBA), CANTHARIS, CARDUUS BENEDICTUS, CEANOTHUS AMERICANUS, CHELIDONIUM MAJUS, CHIONANTHUS VIRGINICA, CINCHONA OFFICINALIS, DIOSCOREA VILLOSA, DOLICHOS PRURIENS, IRIS VERSICOLOR, JUNIPERUS COMMUNIS, NUX VOMICA, PTELEA TRIFOLIATA, URICUM ACIDUM"],"is_original_packager":[true],"manufacturer_name":["VitaminMed, LLC"],"nui":["N0000175806","N0000175807","N0000185371","N0000185375","N0000175629","N0000184306","M0000728","M0006342","M0016962","M0008672","N0000185001","M0516536"],"package_ndc":["70964-0001-1"],"pharm_class_cs":["Allergens [CS]","Dietary Proteins [CS]","Plant Proteins [CS]","Food Additives [CS]","Seed Storage Proteins [CS]"],"pharm_class_epc":["Nitrogen Binding Agent [EPC]","Non-Standardized Food Allergenic Extract [EPC]","Non-Standardized Plant Allergenic Extract [EPC]"],"pharm_class_moa":["Ammonium Ion Binding Activity [MoA]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]"],"product_ndc":["70964-0001"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"spl_id":["71920d36-a413-44e1-9e44-0342d3aea96f"],"spl_set_id":["97824fb3-e2b4-4807-943b-88e26b211bf1"],"substance_name":["MILK THISTLE","CYNARA SCOLYMUS LEAF","SOLIDAGO VIRGAUREA FLOWERING TOP","TARAXACUM OFFICINALE","BENZOIC ACID","BERBERIS VULGARIS ROOT BARK","BRYONIA ALBA ROOT","LYTTA VESICATORIA","CENTAUREA BENEDICTA","CEANOTHUS AMERICANUS LEAF","CHELIDONIUM MAJUS WHOLE","CHIONANTHUS VIRGINICUS BARK","CINCHONA OFFICINALIS BARK","DIOSCOREA VILLOSA TUBER","MUCUNA PRURIENS FRUIT TRICHOME","IRIS VERSICOLOR ROOT","JUNIPER BERRY","STRYCHNOS NUX-VOMICA SEED","PTELEA TRIFOLIATA BARK","URIC ACID"],"unii":["U946SH95EE","B71UA545DE","5405K23S50","39981FM375","8SKN0B0MIM","1TH8Q20J0U","T7J046YI2B","3Q034RO3BT","6L5ZL09795","25B1Y14T8N","7E889U5RNN","S003A158SB","IWY3IWX2G8","3E271BSI0C","X43D4L3DQC","O84B5194RL","269XH13919","5KQR6FTT0D","268B43MJ25"],"upc":["0744309189461"]},"package_label_principal_display_panel":["PACKABE LABEL DISPLAY: M VitaminMed NDC# 70964-0001-1 Advance Plus Homeopathic Medicine 1 FL OZ. 30 ML Advance Plus"],"purpose":["PURPOSE: Benzoicum Acidum – Toxin elimination, Berberis Vulgaris – Liver function, Bryonia – Liver detox support, Cantharis – Bladder inflammation relief, Carduus Benedictus – Gastrointestinal health, Carduus Marianus – Liver function support, Ceanothus Americanus – Spleen support, Chelidonium Majus – Liver drainage, Chionanthus Virginica – Gallbladder support, Cinchona Officinalis – General detoxification, Cynara Scolymus – Liver drainage, Dioscorea Villosa – Digestive support, Dolichos Pruriens – Digestive support, Iris Versicolor – Pancreas health, Juniperus Communis – Kidney drainage, Nux Vomica - Detoxification, Ptelea Trifoliata – Liver detox, Solidago Virgaurea – Kidney support, Taraxacum Officinale – Liver and Kidney detox, Uricum Acidum – Uric acid metabolism"],"questions":["QUESTIONS: Distributed by: VitaminMed 1231 South Myrtle Ave. Clearwater, FL 33756 www.vitaminmed.com Call: 800-949-7875 Monday - Friday 9:00am - 5:00pm Eastern"],"set_id":"97824fb3-e2b4-4807-943b-88e26b211bf1","spl_product_data_elements":["Advance Plus Carduus Marianus, Cynara Scolymus, Solidago Virgaurea, Taraxacum Officinale, Benzoicum Acidum, Berberis Vulgaris, Bryonia (Alba), Cantharis, Carduus Benedictus, Ceanothus Americanus, Chelidonium Majus, Chionanthus Virginica, Cinchona Officinalis, Dioscorea Villosa, Dolichos Pruriens, Iris Versicolor, Juniperus Communis, Nux Vomica, Ptelea Trifoliata, Uricum Acidum MILK THISTLE MILK THISTLE CYNARA SCOLYMUS LEAF CYNARA SCOLYMUS LEAF SOLIDAGO VIRGAUREA FLOWERING TOP SOLIDAGO VIRGAUREA FLOWERING TOP TARAXACUM OFFICINALE TARAXACUM OFFICINALE BENZOIC ACID BENZOIC ACID BERBERIS VULGARIS ROOT BARK BERBERIS VULGARIS ROOT BARK BRYONIA ALBA ROOT BRYONIA ALBA ROOT LYTTA VESICATORIA LYTTA VESICATORIA CENTAUREA BENEDICTA CENTAUREA BENEDICTA CEANOTHUS AMERICANUS LEAF CEANOTHUS AMERICANUS LEAF CHELIDONIUM MAJUS WHOLE CHELIDONIUM MAJUS CHIONANTHUS VIRGINICUS BARK CHIONANTHUS VIRGINICUS BARK CINCHONA OFFICINALIS BARK CINCHONA OFFICINALIS BARK DIOSCOREA VILLOSA TUBER DIOSCOREA VILLOSA TUBER MUCUNA PRURIENS FRUIT TRICHOME MUCUNA PRURIENS FRUIT TRICHOME IRIS VERSICOLOR ROOT IRIS VERSICOLOR ROOT JUNIPER BERRY JUNIPER BERRY STRYCHNOS NUX-VOMICA SEED STRYCHNOS NUX-VOMICA SEED PTELEA TRIFOLIATA BARK PTELEA TRIFOLIATA BARK URIC ACID URIC ACID WATER ALCOHOL"],"version":"4","warnings":["WARNINGS: Stop use and ask a doctor if symptoms worsen or persist for more than a few days. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Do not use if tamper evident seal is broken or missing. Keep tightly closed in a cool, dry place."]}