{"active_ingredient":["Active ingredients Purpose Phenylephrine HCl 0.25% Vasoconstrictor Pramoxine HCl 1% Local anesthetic"],"active_ingredient_table":["<table width=\"60%\"><col width=\"60%\" align=\"left\" valign=\"top\"/><col width=\"40%\" align=\"right\" valign=\"top\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th><content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>Phenylephrine HCl 0.25%</td><td>Vasoconstrictor</td></tr><tr><td>Pramoxine HCl 1%</td><td>Local anesthetic</td></tr></tbody></table>"],"ask_doctor":["Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty urinating due to enlarged prostate gland."],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking a prescription drug for high blood pressure or depression."],"dosage_and_administration":["Directions Remove cap and lift foil safety seal from tube. Adults: When practical, cleanse the affected area with mild soap and warm water, and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product. Apply externally to the affected area with a thin layer up to 4 times daily. Children under 12 years of age: consult a doctor."],"effective_time":"20250205","id":"77adb8f8-6785-4628-88eb-ffeeaa6177ec","inactive_ingredient":["Inactive ingredients Aloe Vera (Aloe Barbadensis) Extract, BHA, Carboxymethylcellulose Sodium, Cetearyl Alcohol, Citric Acid, Edetate Disodium, Glycerin, Glyceryl Stearate, Laureth 23, Methylparaben, Mineral Oil, Panthenol, Propyl Gallate, Propylene Glycol, Propylparaben, Sodium Benzoate, Steareth 2, Steareth 20, Stearyl Alcohol, Tocopherol (Natural Vitamin E), Vitamin E, Water (Purified), White Petrolatum, Xanthan Gum."],"indications_and_usage":["Uses For the temporary relief of anorectal itching, burning and discomfort associated with hemorrhoids, anorectal disorders, inflamed hemorrhoidal tissues, or piles."],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 25 g Tube Box Nikzon ® HEMORRHOIDAL (ANORECTAL) CREAM Temporary relief from: – Pain – Itching – Inflammation Net Wt. 0.9 Oz (25 g) Principal Display Panel - 25 g Tube Box"],"purpose":["Active ingredients Purpose Phenylephrine HCl 0.25% Vasoconstrictor Pramoxine HCl 1% Local anesthetic"],"purpose_table":["<table width=\"60%\"><col width=\"60%\" align=\"left\" valign=\"top\"/><col width=\"40%\" align=\"right\" valign=\"top\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th><content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>Phenylephrine HCl 0.25%</td><td>Vasoconstrictor</td></tr><tr><td>Pramoxine HCl 1%</td><td>Local anesthetic</td></tr></tbody></table>"],"questions":["Questions? 1 877 99 GENOM (43666) Monday to Friday, 8 am to 6 pm Central time."],"set_id":"e144fb04-db3c-4e22-9c9f-8378c7f0ce1f","spl_product_data_elements":["Nikzon Hemorrhoidal PHENYLEPHRINE HYDROCHLORIDE and PRAMOXINE HYDROCHLORIDE PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE PRAMOXINE HYDROCHLORIDE PRAMOXINE ALOE VERA LEAF BUTYLATED HYDROXYANISOLE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED CETOSTEARYL ALCOHOL CITRIC ACID MONOHYDRATE EDETATE DISODIUM GLYCERIN GLYCERYL MONOSTEARATE LAURETH-23 METHYLPARABEN MINERAL OIL PANTHENOL PROPYL GALLATE PROPYLENE GLYCOL PROPYLPARABEN SODIUM BENZOATE STEARETH-2 STEARETH-20 STEARYL ALCOHOL TOCOPHEROL .ALPHA.-TOCOPHEROL WATER PETROLATUM XANTHAN GUM"],"spl_unclassified_section":["Drug Facts","Distributed by: Genomma Lab USA, Inc., Houston, TX, 77027"],"stop_use":["Stop use and ask a doctor if rectal bleeding occurs an allergic reaction occurs the symptom being treated does not subside or if redness, irritation, swelling, pain or other symptoms develop or increase condition worsens or does not improve within 7 days."],"storage_and_handling":["Other information Store at room temperature 15-30°C (59-86°F) Close cap tightly after use."],"version":"3","warnings":["Warnings For external use only Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty urinating due to enlarged prostate gland. Ask a doctor or pharmacist before use if you are taking a prescription drug for high blood pressure or depression. When using this product do not exceed the recommended daily dosage unless directed by a doctor do not put this product into the rectum by using fingers or any mechanical device or applicator. Stop use and ask a doctor if rectal bleeding occurs an allergic reaction occurs the symptom being treated does not subside or if redness, irritation, swelling, pain or other symptoms develop or increase condition worsens or does not improve within 7 days. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product do not exceed the recommended daily dosage unless directed by a doctor do not put this product into the rectum by using fingers or any mechanical device or applicator."]}