{"active_ingredient":["Active ingredient Sodium Monofluorophosphate 0.76% (0.12% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 years of age and older brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician children 2 to 6 years use only a pea sized amount and supervise child's brushing and rinsing (to minimize swallowing) children under 2 years ask a dentist or physician"],"dosage_and_administration_table":["<table width=\"50%\" styleCode=\"Noautorules\"><col width=\"30%\" align=\"left\" valign=\"top\"/><col width=\"70%\" align=\"left\" valign=\"top\"/><tbody><tr styleCode=\"Botrule\"><td styleCode=\"Rrule\">adults and children 2 years of age and older</td><td>brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician</td></tr><tr styleCode=\"Botrule\"><td styleCode=\"Rrule\">children 2 to 6 years</td><td>use only a pea sized amount and supervise child&apos;s brushing and rinsing (to minimize swallowing)</td></tr><tr><td styleCode=\"Rrule\">children under 2 years</td><td>ask a dentist or physician</td></tr></tbody></table>"],"effective_time":"20260713","id":"79bceee3-222f-4872-a467-cdcf87888b7b","inactive_ingredient":["Inactive ingredients Propylene Glycol, Calcium Pyrophosphate, PVP, PEG/PPG-116/66 Copolymer, PEG-12, Glycerin, Flavor, Hydrogen Peroxide, Sodium Lauryl Sulfate, Silica, Tetrasodium Pyrophosphate, Sodium Saccharin, Disodium Pyrophosphate, Sucralose, BHT."],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Colgate Optic White Advanced Icy Fresh"],"generic_name":["SODIUM MONOFLUOROPHOSPHATE"],"is_original_packager":[true],"manufacturer_name":["Colgate-Palmolive Company"],"package_ndc":["35000-977-86","35000-977-32","35000-977-44","35000-977-76"],"product_ndc":["35000-977"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["545626"],"spl_id":["79bceee3-222f-4872-a467-cdcf87888b7b"],"spl_set_id":["f95496e3-11ec-4cd6-b3ee-cf6c657b790b"],"substance_name":["SODIUM MONOFLUOROPHOSPHATE"],"unii":["C810JCZ56Q"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 127 g Tube Carton Colgate ® Anticavity Fluoride Toothpaste OPTIC WHITE ® ADVANCED ICY FRESH PASTE SHIMMERING MINT REMOVES 5 YEARS OF DEEP-SET STAINS* NET WT 4.5 OZ (127 g) ENAMEL SAFE 2% HYDROGEN PEROXIDE PRINCIPAL DISPLAY PANEL - 127 g Tube Carton"],"purpose":["Purpose Anticavity"],"questions":["Questions? 1-800-468-6502"],"set_id":"f95496e3-11ec-4cd6-b3ee-cf6c657b790b","spl_product_data_elements":["Colgate Optic White Advanced Icy Fresh SODIUM MONOFLUOROPHOSPHATE SODIUM MONOFLUOROPHOSPHATE FLUORIDE ION PROPYLENE GLYCOL CALCIUM PYROPHOSPHATE POVIDONE, UNSPECIFIED PEG/PPG-116/66 COPOLYMER POLYETHYLENE GLYCOL 600 GLYCERIN HYDROGEN PEROXIDE SODIUM LAURYL SULFATE SILICON DIOXIDE SODIUM PYROPHOSPHATE SACCHARIN SODIUM SODIUM ACID PYROPHOSPHATE SUCRALOSE BUTYLATED HYDROXYTOLUENE"],"spl_unclassified_section":["Drug Facts","Dist. by: COLGATE-PALMOLIVE COMPANY New York, NY 10022 U.S.A."],"version":"5","warnings":["Warnings Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}