{"description":["CLEAR [ SKIN BLEACHING AND CORRECTOR CREAM ] NET WT 2 OZ (57 G) HYDROQUINONE USP, 4 % RX ONLY AM + PM Dark spots may appear on the surface of your skin, but they usually start deep within the skin's layers. This gentle yet effective formula absorbs into the layers of your skin to deliver prescription - strength hydroquinone, helping to correct the appearance of age and sunspots for a healthier, more even complexion.","BLENDER [ SKIN LIGHTENER AND BLENDING CREAM ] NET WT 2 OZ ( 57 G ) HYDROQUINONE USP, 4 % RX ONLY PM A unique formula containing prescription - strength hydroquinone for the gradual lightening of sun spots, age spots, and other types of hyperpigmentation ( discoloration ). Specially formulated to optimize the delivery of product ingredients in the Nu - Derm System, this skin lightener helps reduce the signs of aging and correct uneven skin tones. May be used with Tretinoin Cream or Refissa as prescribed by a physician. - Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris. - Refissa ( Tretinoin Cream, USP ( Emollient ) 0.05 %] is indicated as an adjunct agent for use in the mitigation ( palliation ) of fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin in patients who do not achieve such palliation using comprehensive skin care and sun avoidance programs. REFISSA DOES NOT ELIMINATE WRINKLES, REPAIR SUN - DAMAGED SKIN, REVERSE PHOTOAGING, or RESTORE A MORE YOUTHFUL DERMAL HISTOLOGIC PATTERN.","SUN SHIELD BROAD SPECTRUM SPF 50 MATTE NET WT 3 OZ ( 85 G ) This sunscreen combines UVB absorption and UVA protection in an elegant matte finish that is non - comedogenic, hypoallergenic, non - acnegenic, and dermatologist tested, Sheer, PABA free, and fragrance free for all skin types."],"dosage_and_administration":["Use daily, in the morning and evening. Squeeze a small amount ( approximately 1 - 2 pea - size amounts ) onto your hand. Apply evenly to the entire face, extedning to the hairline, over the ears, and ending with a feathering motion, or as directed by a physician. If no improvement is seen after three ( 3 ) months of treatment, use of this product should be discontinued. Sun exposure should be limited by using a sunscreen agent, a sun blocking agent, or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening from reoccurring.","Use daily, in the evening. Squeeze a small amount ( approximately 1 - 2 pea sized drops ) onto your hand. Apply evenly to the entire face, or as directed by a physician. If no improvement is seen after three ( 3 ) months of treatment, use of this product should be discontinued. Sun exposure should be limited using a sunscreen agent, a sun blocking agent, or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening from reoccurring.","Directions - apply liberally 15 minutes before sun exposure - use a water resistant sunscreen if swimming or sweating - reapply at least every 2 hours - children under 6 months: ask a doctor - Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: - limit time in the sun, especially from 10 am - 2 pm - wear long- sleeved shirts, pants, hats and sunglasses"],"dosage_forms_and_strengths":["Each gram of Obagi Nu - Derm contains: Active Ingredient Hydroquinone USP, 4 % (40 mg / g) Inactive Ingredients: water, cetyl alcohol, glycerin, sodium lauryl sulfate, stearyl alcohol, lactic acid, tocopheryl acetate, ascorbic acid, sodium metabisulfite, disodium EDTA, methylparaben, BHT, propylparaben saponins, butylparaben","Each gram of Obagi Nu - Derm Blender contains: Active Ingredient Hydroquinone USP, 4 % (40 mg / g ) Inactive Ingredients water, glycerin, cetyl alcohol, PPG - 2 myristyl ether propionate, sodium lauryl sulfate, TEA - salicylate, lactic acid, phenyl trimethicone, tocopheryl acetate, sodium metabisulfite, ascorbic acid, methylparaben, disodium EDTA, propylparaben, BHT"],"effective_time":"20170613","id":"8b8f4397-c0f1-4022-b70a-5328bac54204","indications_and_usage":["The gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation.","The gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation. Specially formulated for blending purposes as part of the Obagi Nu - Derm System.","Uses - helps prevent sunburn - if used as directed with other sun protection measures (see DIRECTIONS), decreases the risk of skin cancer and early skin aging caused by the sun."],"openfda":{},"package_label_principal_display_panel":["copy of label"],"set_id":"eef16915-e2cf-4483-9b99-9efcf012904a","spl_product_data_elements":["Obagi HYDROQUINONE, OCTINOXATE, ZINC OXIDE Obagi Nu-Derm HYDROQUINONE HYDROQUINONE HYDROQUINONE WATER GLYCERIN CETYL ALCOHOL PPG-2 MYRISTYL ETHER PROPIONATE SODIUM LAURYL SULFATE TROLAMINE SALICYLATE LACTIC ACID, UNSPECIFIED FORM PHENYL TRIMETHICONE .ALPHA.-TOCOPHEROL ACETATE SODIUM METABISULFITE ASCORBIC ACID METHYLPARABEN EDETATE DISODIUM PROPYLPARABEN BUTYLATED HYDROXYTOLUENE Obagi Nu-Derm HYDROQUINONE HYDROQUINONE HYDROQUINONE WATER GLYCERIN CETYL ALCOHOL PPG-2 MYRISTYL ETHER PROPIONATE SODIUM LAURYL SULFATE TROLAMINE SALICYLATE LACTIC ACID, UNSPECIFIED FORM PHENYL TRIMETHICONE .ALPHA.-TOCOPHEROL ACETATE SODIUM METABISULFITE ASCORBIC ACID METHYLPARABEN EDETATE DISODIUM PROPYLPARABEN BUTYLATED HYDROXYTOLUENE Obagi OCTINOXATE, ZINC OXIDE OCTINOXATE OCTINOXATE ZINC OXIDE ZINC OXIDE CYCLOMETHICONE 5 WATER PEG-10 DIMETHICONE (600 CST) PENTYLENE GLYCOL STEARYL ALCOHOL POLYOXYL 20 CETOSTEARYL ETHER PHENYL TRIMETHICONE PEG-40 STEARATE SODIUM DIHYDROXYCETYL PHOSPHATE HYDROGENATED PALM GLYCERIDES CITRIC ACID MONOHYDRATE CETOSTEARYL ALCOHOL .ALPHA.-TOCOPHEROL ACETATE 1,2-HEXANEDIOL CAPRYLYL GLYCOL TROPOLONE CHLORPHENESIN XANTHAN GUM POTASSIUM SORBATE SODIUM BENZOATE TETRAHEXYLDECYL ASCORBATE UBIDECARENONE EDETATE DISODIUM METHYLISOTHIAZOLINONE HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (100000 MPA.S AT 1.5%) SQUALANE POLYSORBATE 60"],"spl_unclassified_section":["See enclosed Package Insert full prescribing information. Rx ONLY. FOR EXTERNAL USE ONLY.","see enclosed Package Insert for full prescribing information. Rx ONLY. FOR EXTERNAL USE ONLY.","Travel Bag and Patient Instruction Guide","Active Ingredients Octinoxate 7.5 % Zinc Oxide 10 %","Purpose Sunscreen","Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.","Inactive Ingredients 1,2 hexanediol, caprylyl glycol, ceteareth - 20, cetearyl alcohol, chlorphenesin, citric acid, cyclopentasiloxane, dimethicone, dimethicone crosspolymer - 3, disodium EDTA, glycerin, hydrogenated palm glycerides, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, methylisothiaszolinone, PEG - 40 stearate, pentylene glycol, pheoxyethanol, phenyl trimethicone, polysilicone - 11, polysorbate 60, potassium sorbate, sodium benzoate, sodium dihydroxycetyl phosphate, sodium polyacrylate, squalane, stearyl alcohol, tetrahexyldecyl ascorbate, tropolone, water, xanthan gum","Questions or Comments? 1.800.636.7546 Monday - Friday 9 am - 4 pm Pacific Time"],"storage_and_handling":["Store at controlled room temperature 15 C - 25 C ( 59 F - 77 F )","Other Information - store at controlled room temperature 15 C - 25 C (59 F - 77 F ) - protect this product from excessive heat and direct sun"],"version":"2","warnings":["Avoid contact with eyes, nose, mouth and lips. In case of accidental contact, patient should rinse thoroughly with water and contact a physician. Sunscreen use is an essential part of hydroquinone therapy because even minimal amounts of sunlight exposure sustains melanocytic activity. Contains sodium metabisulfite, a sulfite that may cause allergic - type reactions including anaphylactic symptoms and life - threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.","Avoid contact with eyes, nose, mouth and lips. In case of accidental contact, patient should rinse thoroughly with water and contact a physician. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity. Contains sodium metabisulfite, a sulfite that may cause allergic - type reactions including anaphylactic symptoms and life- threatening or less severe asthamtic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.","Warnings For external use only Do not use on damaged or broken skin Stop use and ask a doctor if rash occurs When using this product, keep out of eyes. Rinse with water to remove. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."]}