{"active_ingredient":["Drug Facts Active ingredients (in each Softgel) Acetaminophen 325 mg............. Pain reliever/Fever reducer Dextromethorphan HBr 15 mg..... Cough suppressant Doxylamine succinate 6.25 mg ..... Antihistamine"],"ask_doctor":["Ask a doctor before use if you have • liver disease •glaucoma •cough that occurs with too much phlegm (mucus) • a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema • trouble urinating due to enlarged prostate gland"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are •taking sedatives or tranquilizers •taking the blood thinning drug warfarin"],"do_not_use":["Do not use • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist •if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product •to make a child sleep"],"dosage_and_administration":["Directions •take only as directed (see Warning) •do not exceed 4 doses per 24 hours Adults & Children 12 years & over: 2 soft gels with water every 6 hours Children 4 to under 12 years: Ask a doctor Children under 4 years: Do not use"],"effective_time":"20260510","id":"8f4959ca-8471-47a4-bd2d-f22d639396cf","inactive_ingredient":["Inactive ingredients D&C Yellow # 10, FD&C Blue # 1, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, Sorbitol sorbitan solution, Titanium dioxide."],"indications_and_usage":["Uses Temporarily relieves common cold/flu symptoms:"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of accidental overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for aduits as well as for children, even if you do not notice any signs or symptoms."],"openfda":{"application_number":["M012"],"brand_name":["Night Time Cold and Flu relief liquid filled softgels"],"generic_name":["ACETAMINOPHEN,DEXTROMETHROPHAN HBR,DOXYLAMINE SUCCINATE"],"is_original_packager":[true],"manufacturer_name":["AptaPharma Inc."],"package_ndc":["76281-603-03"],"product_ndc":["76281-603"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1094549"],"spl_id":["8f4959ca-8471-47a4-bd2d-f22d639396cf"],"spl_set_id":["d61e2186-8b59-45f9-96ec-83430a0fe0cb"],"substance_name":["ACETAMINOPHEN","DEXTROMETHORPHAN HYDROBROMIDE","DOXYLAMINE SUCCINATE"],"unii":["362O9ITL9D","9D2RTI9KYH","V9BI9B5YI2"]},"other_safety_information":["Other information •Store at room temperature 20-25°C (68-77°F) •avoid excessive heat"],"package_label_principal_display_panel":["Product Label: AP SAFE Night time cold/flu Softgels ------------------------------------------------------ AP SAFE​ ® Nighttime *Compare to the active ingredients Cold/Flu Relief In Vicks​ ​® Nyquil ​™ Cold & Flu Nighttime Relief LiquiCaps™ Acetaminophen Dextromethorphan HBr/Doxylamine Succinate 24 Softgels Manufactured by AptaPharma Inc., 1533 Union Ave., Pennsauken, NJ 08110 • This product is not manufactured or distributed by Procter & Gamble, owner of the registered trademark Vicks ​® Nyquil ​™ Liquicaps ​™ TAMPER EVIDENT:DO NOT USE IF CARTON IS OPENED OR IF BLISTER UNIT IS TORN, BROKEN OR SHOWS ANY SIGNS OF TAMPERING KEEP OUTER CARTON FOR COMPLETE WARNING AND PRODUCT INFORMATION. resRes 603"],"pregnancy_or_breast_feeding":["If pregnant or breast feeding , ask a health professional before use."],"purpose":["• cough due to minor throat & bronchial irritation • sore throat • headache • minor aches & pain • fever • runny nose & sneezing"],"questions":["Questions? Call Weekdays from 9:30 AM to 4:30 PM EST at 1-877-798-5944"],"set_id":"d61e2186-8b59-45f9-96ec-83430a0fe0cb","spl_product_data_elements":["Night Time Cold and Flu relief liquid filled softgels Acetaminophen,Dextromethrophan HBR,Doxylamine Succinate ACETAMINOPHEN ACETAMINOPHEN DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN DOXYLAMINE SUCCINATE DOXYLAMINE D&C YELLOW NO. 10 FD&C BLUE NO. 1 GELATIN GLYCERIN POLYETHYLENE GLYCOL, UNSPECIFIED POVIDONE PROPYLENE GLYCOL WATER SORBITOL SORBITAN TITANIUM DIOXIDE 603"],"stop_use":["Stop use and ask a doctor if •pain or cough gets worse or lasts more than 7 days •fever gets worse or lasts more than 3 days •redness or swelling is present •new symptoms occur •cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.​"],"version":"1","warnings":["Warnings Liver warning : This product contains acetaminophen. Severe liver damage may occur if you take: •more than 4 doses in 24 hours, which is the maximum daily amount for this product •with other drugs containing acetaminophen •3 or more alcoholic drinks daily while using this product. Allergy alert : Acetaminophen may cause severe skin reactions. Symptoms may include: •skin reddening •blisters •rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning : If sore throat is severe, lasts for more than 2 days, occurs with or is followed by fever, headache, rash, nausea or vomiting, consult a doctor promptly."],"when_using":["When using this product do not use more than directed .• excitability may occur, especially in children, • marked drowsiness may occur •avoid alcoholic drinks •be careful when driving a motor vehicle or operating machinery •alcohol, sedatives, and tranquilizers may increase drowsiness","•When using other Daytime or Nighttime products, carefully read each label to ensure correct dosing."]}