{"active_ingredient":["Active ingredients (in each tablet) Acetaminophen 250 mg Chlorpheniramine maleate 2 mg Dextromethorphan hydrobromide 10 mg Phenylephrine hydrochloride 5 mg"],"ask_doctor":["Ask a doctor before use if you have ● liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● glaucoma ● cough with excessive phlegm (mucus) ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema ● a sodium restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are ● taking the blood thinning drug warfarin ● taking sedatives or tranquilizers"],"do_not_use":["Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions · do not take more than the recommended dose · adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 8 tablets in 24 hours or as directed by a doctor. · children under 12 years: do not use"],"effective_time":"20191126","id":"9846ff32-284b-5666-e053-2995a90afa2b","inactive_ingredient":["Inactive ingredients acesulfame potassium, anhydrous citric acid, aspartame, FD&C red #40, flavors, magnesium stearate, maltodextrin, mannitol, saccharin sodium, sodium bicarbonate"],"indications_and_usage":["Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · sore throat · runny nose · sneezing · nasal and sinus congestion · temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms"],"openfda":{},"other_safety_information":["Other information ● each tablet contains: sodium 416 mg ● Phenylketonurics: Contains Phenylalanine 5.6 mg Per Tablet ● store at room temperature. Avoid excessive heat."],"package_label_principal_display_panel":["Alka-Seltzer PLUS® SEVERE Cold & Flu CITRUS Acetaminophen / Pain Reliever-Fever Reducer Chlorpheniramine Maleate / Antihistamine Dextromethorphan HBr / Cough Suppressant Phenylephrine Hydrochloride / Nasal Decongestant Fever & Body Ache Cough Nasal Congestion Runny Nose Sore Throat 20 EFFERVESCENT TABLETS Carton 20 count"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding , ask a health professional before use."],"purpose":["Purposes Pain reliever/fever reducer Antihistamine Cough suppressant Nasal decongestant"],"questions":["Questions or comments? 1-800-986-0369 (Mon-Fri 9AM - 5PM EST)"],"set_id":"531a86b3-2915-6d55-e054-00144ff88e88","spl_product_data_elements":["Alka-Seltzer Plus Severe Cold and Flu Acetaminophen, Chlorpheniramine maleate, Dextromethorphan hydrobromide, Phenylephrine hydrochloride ASPIRIN ASPIRIN DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE ACESULFAME POTASSIUM ANHYDROUS CITRIC ACID FD&C RED NO. 40 CHLORPHENIRAMINE MALEATE CHLORPHENIRAMINE MAGNESIUM STEARATE MALTODEXTRIN MANNITOL SACCHARIN SODIUM SODIUM BICARBONATE ASP;FLU"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs"],"version":"3","warnings":["Warnings Liver warning : This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children"],"when_using":["When using this product ● do not exceed recommended dosage ● may cause marked drowsiness ● avoid alcoholic drinks ● alcohol, sedatives, and tranquilizers may increase drowsiness ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children"]}