{"active_ingredient":["Active ingredients (in each 30 mL) Acetaminophen 650 mg Dextromethorphan hydrobromide 30 mg Doxylamine succinate 12.5 mg"],"ask_doctor":["Ask a doctor before use if you have liver disease glaucoma cough with excessive phlegm (mucus) a breathing problem such as emphysema or chronic bronchitis difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma, or emphysema a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers"],"do_not_use":["Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug ontains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients in children under 12 years of age"],"dosage_and_administration":["Directions use only the enclosed green dosing cup designed for use with this product. Do not use any other dosing device. do not take more than the recommended dose do not exceed 4 doses in 24 hours or as directed by a doctor adults and children 12 years and over: take 30 mL in the green dosing cup provided every 6 hours children under 12 years: do not use when using other Alka-Seltzer Plus® products, read each label carefully to ensure correct dosing and only use the dosing cup accompanying that specific product"],"effective_time":"20191206","id":"9906c159-7bb6-e5f0-e053-2995a90ab6ea","inactive_ingredient":["Inactive ingredients alcohol, anhydrous citric acid, edetate disodium, FD&C Red #40, flavors, glycerin, polyethylene glycol, povidone, propionic acid, propylene glycol, purified water, sodium benzoate, sodium citrate, sorbitol solution, sucralose"],"indications_and_usage":["Uses temporarily relieves these symptoms due to a cold or flu: minor aches and pains  headache  sore throat runny nose  sneezing cough due to minor throat and bronchial irritation controls the impulse to cough to help you get to sleep temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{},"other_safety_information":["Other information each 30 mL contains : sodium 54 mg store at 20 - 25°C (68 - 77°F). Avoid excessive heat above 40°C (104°F)."],"package_label_principal_display_panel":["aspliquid"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purposes Acetaminophen 650 mg Pain reliever/fever reducer Dextromethorphan hydrobromide 30 mg Cough suppressant Doxylamine succinate 12.5 mg Antihistamine"],"purpose_table":["
Acetaminophen 650 mg Pain reliever/fever reducer
Dextromethorphan hydrobromide 30 mg Cough suppressant
Doxylamine succinate 12.5 mg Antihistamine
"],"questions":["Questions or comments?"],"set_id":"46c9ba91-78ee-680f-e054-00144ff8d46c","spl_product_data_elements":["Alka-Seltzer Plus Severe Cold and Cough Night Acetaminophen, Dextromethorphan hydrobromide, Doxylamine succinate ACETAMINOPHEN ACETAMINOPHEN DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN DOXYLAMINE SUCCINATE DOXYLAMINE ALCOHOL FD&C RED NO. 40 POLYETHYLENE GLYCOL, UNSPECIFIED SODIUM CITRATE POVIDONE EDETATE DISODIUM GLYCERIN WATER SODIUM BENZOATE ANHYDROUS CITRIC ACID"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition."],"version":"3","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4 doses in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy Alert: acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: skin reddening  blisters  rash  hives facial swelling  asthma (wheezing)  shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children.","Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4 doses in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product","Allergy Alert: acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: skin reddening  blisters  rash  hives facial swelling  asthma (wheezing)  shock If a skin or general allergic reaction occurs, stop use and seek medical help right away.","Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.","Do not use to sedate children."],"when_using":["When using this product may cause marked drowsiness alcohol, sedatives, and tranquilizers may increase drowsiness avoid alcoholic drinks be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children"]}