{"active_ingredient":["Active ingredient Aspirin Suppositories, USP 300 mg (5 grains) Each suppository contains 300 mg (5 grains) of aspirin."],"dosage_and_administration":["Directions Remove suppository from plastic packet and insert into the rectum as far as possible. Adult: One suppository every 4 hours for no more than 10 days or as directed by a physician. Children under 12 years of age: Consult a physician."],"effective_time":"20220430","id":"a6ca751c-7438-4a0f-adae-d176f73f4915","inactive_ingredient":["ALCOHOL WARNING: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take aspirin or other pain relievers/fever reducers. Aspirin may cause stomach bleeding. Manufactured by Padagis Minneapolis, MN 55427 Rev 04-22"],"indications_and_usage":["Caution: Suppositories sealed in imprinted plastic packet. Do not use if imprinted packet is opened or damaged. Store in a cool place 8° - 15°C (46° - 59°F) or refrigerate."],"keep_out_of_reach_of_children":["Keep this and all drugs out of the reach of children. In case of accidental ingestion, seek professional assistance or contact a poison control center immediately."],"openfda":{"brand_name":["aspirin"],"generic_name":["ASPIRIN"],"is_original_packager":[true],"manufacturer_name":["Padagis US LLC"],"nui":["N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["0574-7034-12"],"pharm_class_cs":["Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["0574-7034"],"product_type":["HUMAN OTC DRUG"],"route":["RECTAL"],"rxcui":["198464"],"spl_id":["a6ca751c-7438-4a0f-adae-d176f73f4915"],"spl_set_id":["cce244aa-cd79-49c8-b68e-267f2bd0ef67"],"substance_name":["ASPIRIN"],"unii":["R16CO5Y76E"]},"package_label_principal_display_panel":["Package/Label Principal Display Panel – 300 mg NDC 0574-7034-12 Aspirin Suppositories, USP 300 mg (5 grains) For relief of pain and reduction of fever UNIT DOSE 12 Suppositories carton 300mg"],"purpose":["Indications: For the relief of minor aches, pains and headache and for reduction of fever."],"set_id":"cce244aa-cd79-49c8-b68e-267f2bd0ef67","spl_product_data_elements":["aspirin aspirin ASPIRIN ASPIRIN HYDROGENATED PALM KERNEL OIL SILICON DIOXIDE"],"version":"6","warnings":["Warnings CHILDREN AND TEENAGERS WHO HAVE OR ARE RECOVERING FROM CHICKEN POX, FLU SYMPTOMS, OR FLU SHOULD NOT USE THIS PRODUCT. IF NAUSEA, VOMITING, OR FEVER OCCUR, CONSULT A DOCTOR BECAUSE THESE SYMPTOMS COULD BE AN EARLY SIGN OF REYE SYNDROME, A RARE BUT SERIOUS ILLNESS. As with any drug, if you are pregnant or nursing a baby, seek the advice of a health professional before using this product. IT IS ESPECIALLY IMPORTANT NOT TO USE ASPIRIN DURING THE LAST 3 MONTHS OF PREGNANCY UNLESS SPECIFICALLY DIRECTED TO DO SO BY A DOCTOR BECAUSE IT MAY CAUSE PROBLEMS IN THE UNBORN CHILD OR COMPLICATIONS DURING DELIVERY."]}