{"active_ingredient":["Active ingredients (in each suppository) Cocoa butter 88.44% Phenylephrine HCl 0.25%"],"ask_doctor":["Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • difficulty in urination due to enlargement of the prostate gland"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression."],"dosage_and_administration":["Directions • adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before insertion of this product. • detach one suppository from the strip; remove the foil wrapper before inserting into the rectum as follows: • hold suppository with rounded end up • see illustrations: carefully separate foil tabs by inserting tip of fingernail at end marked “peel down” • slowly and evenly peel apart (do not tear) foil by pulling tabs down both sides, to expose the suppository • remove exposed suppository from wrapper • insert one suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement • children under 12 years of age: ask a doctor Other information • store at 20-25°C (68-77°F)"],"effective_time":"20241105","id":"a91eba25-ebee-4b6e-855f-d304b4a64ed1","inactive_ingredient":["Inactive ingredients methylparaben, propylparaben, topical starch Questions? Call 1-888-547-7400"],"indications_and_usage":["Uses • helps relieve the local itching and discomfort associated with hemorrhoids • temporarily relieves burning and shrinks hemorrhoidal tissue • temporarily provides a coating for relief of anorectal discomforts • temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)"],"openfda":{},"package_label_principal_display_panel":["Package/Label Principal Display Panel Compare to active ingredients in Preparation H® Hemorrhoidal Suppositories hemorrhoidal suppositories helps shrink swelling and provide relief helps relieve itching, burning and discomfort reduces swollen hemorrhoidal tissues 12 SUPPOSITORIES 12 COUNT Up and Up Hemorrhoidal Suppositories Image 1 Up and Up Hemorrhoidal Suppositories Image 2"],"pregnancy_or_breast_feeding":["If pregnant or breast feeding, ask a health professional before use."],"purpose":["Purposes Protectant Vasoconstrictor"],"questions":["Questions? Call 1-888-547-7400"],"set_id":"d56ecdfd-5c77-41e0-a42c-d135d9f0a817","spl_product_data_elements":["up and up hemorrhoidal cocoa butter, phenylephrine HCl COCOA BUTTER COCOA BUTTER PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE METHYLPARABEN PROPYLPARABEN STARCH, CORN light"],"stop_use":["Stop use and ask a doctor if • bleeding occurs • condition worsens or does not improve within 7 days"],"storage_and_handling":["Other information • store at 20-25°C (68-77°F)"],"version":"4","warnings":["Warnings For rectal use only Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • difficulty in urination due to enlargement of the prostate gland Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression. When using this product do not exceed the recommended daily dosage unless directed by a doctor Stop use and ask a doctor if • bleeding occurs • condition worsens or does not improve within 7 days If pregnant or breast feeding, ask a health professional before use."],"when_using":["When using this product do not exceed the recommended daily dosage unless directed by a doctor"]}