{"active_ingredient":["Active ingredients (in each caplet) Acetaminophen 250 mg Aspirin 250 mg (NSAID)* Caffeine 65 mg *nonsteroidal anti-inflammatory drug"],"dosage_and_administration":["Directions • do not use more than directed (see overdose warning) • drink a full glass of water with each dose • adults and children 12 years and over: take 2 caplets every 6 hours; not more than 8 caplets in 24 hours • children under 12: ask a doctor"],"effective_time":"20201215","id":"b686307a-93bc-33aa-e053-2a95a90adbb3","inactive_ingredient":["Inactive ingredients cellulose, fractionated coconut oil, hypromellose, magnesium silicate, maltodextrin, polydextrose, povidone, silica, starch, stearic acid, titanium dioxide."],"indications_and_usage":["Use temporarily relieves minor aches and pains"],"keep_out_of_reach_of_children":["Keep out of reach of children. Overdose Warning: Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{},"package_label_principal_display_panel":["Package label NDC 68016-110-00 *Compare to the active ingredients in Excedrin Premier Value Extra Strength PAIN RELIEVER Acetaminophen 250mg Aspirin 250mg Caffeine 65mg 100 Caplets pv226"],"purpose":["Purposes Pain Reliever Pain reliever aid"],"set_id":"07097099-a2e8-4b8d-e054-00144ff88e88","spl_product_data_elements":["Extra Strength Pain Reliever Acetaminophen, Aspirin, Caffeine MAGNESIUM SILICATE MALTODEXTRIN CELLULOSE, MICROCRYSTALLINE POLYDEXTROSE POVIDONE SILICON DIOXIDE STEARIC ACID ACETAMINOPHEN ACETAMINOPHEN ASPIRIN ASPIRIN TITANIUM DIOXIDE CAFFEINE CAFFEINE MEDIUM-CHAIN TRIGLYCERIDES HYPROMELLOSES STARCH, CORN WHITE Capsule GC226"],"storage_and_handling":["Other Information store at controlled room temperature 15° - 25°C (59°-77°F) read all product information before using"],"version":"3","warnings":["Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include: • hives • facial swelling • asthma (wheezing) • shock Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take • more than directed • with other drugs containing acetaminophen • 3 or more alcoholic drinks every day while using this product Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you • are age 60 or older • have had stomach ulcers or bleeding problems • take a blood thinning (anticoagulant) or steroid drug • take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) • have 3 or more alcoholic drinks every day while using this product • take more or for a longer time than directed Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heartbeat. Do not use • if you have ever had an allergic reaction to aspirin or any other pain reliever/fever reducer • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask a doctor before use if • you have liver disease • stomach bleeding warning applies to you • you have a history of stomach problems, such as heartburn • you have high blood pressure, heart disease, liver cirrhosis, or kidney disease • you are taking a diuretic • you have asthma Ask a doctor or pharmacist before use if you are taking • any other drug containing an NSAID (prescription or nonprescription) • a blood thinning (anticoagulant) or steroid drug • a prescription drug for diabetes, gout, or arthritis • any other drug, or are under a doctor’s care for any serious condition Stop use and ask a doctor if • an allergic reaction occurs. Seek medical help right away. • you experience any of the following signs of stomach bleeding: feel faint vomit blood have bloody or black stools have stomach pain that does not get better • ringing in the ears or loss of hearing occurs • painful area is red or swollen • pain gets worse or lasts for more than 10 days • fever gets worse or lasts more than 3 days • any new symptoms appear If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. Overdose Warning: Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."]}