{"active_ingredient":["Active ingredient Salicylic Acid USP, 2%"],"dosage_and_administration":["Directions Wet affected area, apply, and rinse well. Because excessive drying of the skin can occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a physician If bothersome dryness occurs, reduce application to once a day or every other day."],"effective_time":"20240725","id":"d8528811-6b8f-4332-96c2-753657502234","inactive_ingredient":["Inactive ingredients Cocamidopropyl Betaine, Disodium EDTA, Fragrance, Glycolic Acid, Linoleamidopropyl PG-Dimonium Chloride Phosphate, PEG-150 Distearate, Polysorbate-20, Propylene Glycol, Purified Water, Red #40 [CI-16035], Sodium C12-15 Pareth-15 Sulfonate, Sodium C14-16 Olefin Sulfonate, Triethanolamine, Yellow #5 [CI-19140]."],"indications_and_usage":["Uses Skin cleanser for the treatment of acne."],"keep_out_of_reach_of_children":["Keep out of the reach of children. If swallowed, get medical help or contact a Poison Control Center. Sunscreen use is recommended with any glycolic acid product and for an additional week thereafter because some individuals may be more sensitive to sunlight."],"openfda":{"application_number":["M006"],"brand_name":["Replenix Gly-Sal 2-2"],"generic_name":["SALICYLIC ACID"],"is_original_packager":[true],"manufacturer_name":["Topiderm, Inc."],"package_ndc":["51326-925-01"],"product_ndc":["51326-925"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["562600"],"spl_id":["d8528811-6b8f-4332-96c2-753657502234"],"spl_set_id":["6c6bbedc-e2ee-46a0-8800-e356bdd262b0"],"substance_name":["SALICYLIC ACID"],"unii":["O414PZ4LPZ"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 200 ml Bottle Label COMPLIMENTS OF TOPIX PHARMACEUTICALS, INC Gly/Sal 2-2 Pore Refining Cleanser Glycolic Acid 2% Salicylic Acid USP, 2% Net 6.7 fl. oz. (200 ml) Available Custom Branded 800.445.2595 c.service@topixpharm.com PRINCIPAL DISPLAY PANEL - 200 ml Bottle Label"],"purpose":["Purpose Acne medication"],"set_id":"6c6bbedc-e2ee-46a0-8800-e356bdd262b0","spl_product_data_elements":["Replenix Gly-Sal 2-2 salicylic acid SALICYLIC ACID SALICYLIC ACID COCAMIDOPROPYL BETAINE EDETATE DISODIUM GLYCOLIC ACID LINOLEAMIDOPROPYL PROPYLENE GLYCOL-DIMONIUM CHLORIDE PHOSPHATE PEG-150 DISTEARATE POLYSORBATE 20 PROPYLENE GLYCOL WATER FD&C RED NO. 40 SODIUM C12-15 ALKETH-15 SULFONATE SODIUM C14-16 OLEFIN SULFONATE TROLAMINE FD&C YELLOW NO. 5"],"spl_unclassified_section":["Drug Facts"],"version":"1","warnings":["Warnings For external use only Keep away from eyes, lips, and mouth. Using other topical medications, while using this product or immediately thereafter, may increase dryness or irritation. If this occurs discontinue use and see your doctor. Keep out of the reach of children. If swallowed, get medical help or contact a Poison Control Center. Sunscreen use is recommended with any glycolic acid product and for an additional week thereafter because some individuals may be more sensitive to sunlight."]}